logical_unit_id string | example_id string | messages list | task_type string | split string | graph_unit_id string | difficulty int32 | hop_count int32 | source_node_ids list | source_edge_ids list | source_triples list | answer_entity_ids list | relation_ids list | negative_strategy string | generation_mode string | prompt_version string | generator_model string | validation_results string | kg_name string | kg_version string | kg_sha256 string | sources list | licenses list | metadata string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
a127e93b2f0f4d581a44cf64e67052e2e715e5ec770c8b2f17248587aea28ef7 | e8e120ee53ce54579bb78fee20ca050aaf4ad5f2b7870c88d11159be53f8d63f | [
{
"content": "Which compound is included in the pharmacologic class of Cytochrome P450 3A5 Inhibitors?",
"role": "user"
},
{
"content": "Boceprevir",
"role": "assistant"
}
] | atomic_qa | train | bb78c63134afa3a8963d925c70abb1af301fb13141bd4a72eb883473bf9856f3 | 1 | 1 | [
"Pharmacologic Class::N0000190115",
"Compound::DB08873"
] | [
"c2cddcb740ff6b3b5569b554fb478eb422f63f20718befd3bc4da4fb0e4d292e"
] | [
{
"edge_id": "c2cddcb740ff6b3b5569b554fb478eb422f63f20718befd3bc4da4fb0e4d292e",
"source_id": "Pharmacologic Class::N0000190115",
"source_name": "Cytochrome P450 3A5 Inhibitors",
"relation_id": "Pharmacologic Class-includes-Compound",
"target_id": "Compound::DB08873",
"target_name": "Bocepre... | [
"Compound::DB08873"
] | [
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"DrugCentral",
"FDA via DrugCentral"
] | [
"CC BY 4.0",
"CC BY-NC 4.0"
] | {"known_id": "Pharmacologic Class::N0000190115", "query_direction": "forward", "structural_split_key": "07b62978b0b813b48746e190312d5683c178b26f142ea1d1bb3c261f3827e577"} |
79183a1773bd15496dd5f3954f91c97038d29d071c9ec357b563f46211880104 | c70bb9d429480fc7ee1d0c2a2dc679631d72a1530398cad8bcb26145fce9fb9c | [
{
"content": "What is the pharmacologic class of Efavirenz?",
"role": "user"
},
{
"content": "Cytochrome P450 2C19 Inhibitors",
"role": "assistant"
}
] | atomic_qa | train | 829a758c5b9badfd11eee582fa0ab2d9f84394a0e7e586ef1eef8cd4176218b6 | 1 | 1 | [
"Pharmacologic Class::N0000182140",
"Compound::DB00625"
] | [
"23c26bf81859afb3cc4dec83e591fa5deb457ad62b8c15b718bce213b7465b4f"
] | [
{
"edge_id": "23c26bf81859afb3cc4dec83e591fa5deb457ad62b8c15b718bce213b7465b4f",
"source_id": "Pharmacologic Class::N0000182140",
"source_name": "Cytochrome P450 2C19 Inhibitors",
"relation_id": "Pharmacologic Class-includes-Compound",
"target_id": "Compound::DB00625",
"target_name": "Efavir... | [
"Pharmacologic Class::N0000182140"
] | [
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"DrugCentral",
"FDA via DrugCentral"
] | [
"CC BY 4.0",
"CC BY-NC 4.0"
] | {"known_id": "Compound::DB00625", "query_direction": "inverse", "structural_split_key": "c2a2d7c41a430442feed8249b9e61b14f8bbf4fa765587d9b553735c55b8399e"} |
1648d2386546300af614791874e5aadb810833ec66e9585e93b4430ef2f06096 | e585664870daaf7fbf50b1b085ae93aa0519dd261989e9b79a25e5321c47789f | [
{
"content": "In the context of colon cancer, which gene is upregulated?",
"role": "user"
},
{
"content": "CCT2",
"role": "assistant"
}
] | atomic_qa | train | 6e941d5df21c021ede8e7c4ccc9b2350d4fd77c8fa05b1bf1b8f079b3fe00d6c | 1 | 1 | [
"Disease::DOID:219",
"Gene::10576"
] | [
"d9af2def5f0bea499643fa058d93a4e2d39a5d940fe578027ab1a918a0434b2c"
] | [
{
"edge_id": "d9af2def5f0bea499643fa058d93a4e2d39a5d940fe578027ab1a918a0434b2c",
"source_id": "Disease::DOID:219",
"source_name": "colon cancer",
"relation_id": "Disease-upregulates-Gene",
"target_id": "Gene::10576",
"target_name": "CCT2"
}
] | [
"Gene::10576"
] | [
"Disease-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:219", "query_direction": "forward", "structural_split_key": "3ffded6524e6f84e9181ac0633f59ed0c291b5b72598d2a4d8bbdbc07569b3d3"} |
e8fe1405eb9f90a0ce5990da67c6789aa50ab2b7dece19f756d7a575619771dd | 649c984a36938ad863340f3a7f4815ca67abc51f9671cc55f8aee9cf2fb4626f | [
{
"content": "Delavirdine binds the protein product of which gene?",
"role": "user"
},
{
"content": "CYP2C9",
"role": "assistant"
}
] | atomic_qa | train | bc72043e3c42e4829f595685e47f9a1e0d1b2b49da86ea225aaf6c7c9f45a358 | 1 | 1 | [
"Compound::DB00705",
"Gene::1559"
] | [
"1404a4056c2c892786f17e598a4f7d828dfad5bc6a79dc940551357b79ae9645"
] | [
{
"edge_id": "1404a4056c2c892786f17e598a4f7d828dfad5bc6a79dc940551357b79ae9645",
"source_id": "Compound::DB00705",
"source_name": "Delavirdine",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::1559",
"target_name": "CYP2C9"
}
] | [
"Gene::1559"
] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 9} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00705", "query_direction": "forward", "structural_split_key": "cfedd30ff7632fd174abe1fe7ba851511534d57ad1517fdc3333e12c4024be19"} |
7acab2c9c370a131cc2a7f23d855771108f82ea2b80d3eadaa91ac662d05f504 | 1548bdedc86daea65f39561455b0d1dd519aaa0cbc0fe2924f8db1c426f61742 | [
{
"content": "What symptoms can Parkinson's disease present with?\n\nassistant_content",
"role": "user"
},
{
"content": "Restless Legs Syndrome",
"role": "assistant"
}
] | atomic_qa | train | 92567f05c8a448aecbb087c54af0c3dc8ba8e7cc74938039f382751e5c53e930 | 1 | 1 | [
"Disease::DOID:14330",
"Symptom::D012148"
] | [
"0b805aa70d92807690d4f8ddec8ed82f781d1e5a2d87b5723af84b2c6c0d5d49"
] | [
{
"edge_id": "0b805aa70d92807690d4f8ddec8ed82f781d1e5a2d87b5723af84b2c6c0d5d49",
"source_id": "Disease::DOID:14330",
"source_name": "Parkinson's disease",
"relation_id": "Disease-presents-Symptom",
"target_id": "Symptom::D012148",
"target_name": "Restless Legs Syndrome"
}
] | [
"Symptom::D012148"
] | [
"Disease-presents-Symptom"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 11} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"MeSH"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:14330", "query_direction": "forward", "structural_split_key": "86de5bfc639fce4151fbc140e5298a348670ced35f041fdee37812b765c94e37"} |
b990a2775302914a1dc8a626ab9cd0a48a17b0d4ffdf7e338c45b5bb628ce202 | c64410cd052fb4bd7597f94a2e65e1e07f29ad8d87bfa189f0932670a50c65eb | [
{
"content": "What compound is a disease-modifying treatment for psoriasis?",
"role": "user"
},
{
"content": "Clobetasol propionate",
"role": "assistant"
}
] | atomic_qa | train | 116d018fb0a743f9c8e12162229e24ee21ce3cc78ff601f82f0dea85f1d65563 | 1 | 1 | [
"Compound::DB01013",
"Disease::DOID:8893"
] | [
"6b3680c5a1dfe3391d223d318826cb885af3401e217ce8891c417674ad4e6ad8"
] | [
{
"edge_id": "6b3680c5a1dfe3391d223d318826cb885af3401e217ce8891c417674ad4e6ad8",
"source_id": "Compound::DB01013",
"source_name": "Clobetasol propionate",
"relation_id": "Compound-treats-Disease",
"target_id": "Disease::DOID:8893",
"target_name": "psoriasis"
}
] | [
"Compound::DB01013"
] | [
"Compound-treats-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 10} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:8893", "query_direction": "inverse", "structural_split_key": "027e84a3cfd47d9f132329c32629988e50e9d9f17478e6af12ae409ad9fc7f3b"} |
e683899b4c19e4a7679f923b65d7b6378d0b563482eb81522619297538ba9fb9 | ac8990aa0fc36d5a747839cd7d6284731f4b0de3d3ccaff4b1116edc87496018 | [
{
"content": "Which compound is chemically similar to Carbamazepine?",
"role": "user"
},
{
"content": "Promethazine",
"role": "assistant"
}
] | atomic_qa | train | b32c116f8f55ebe0ebe23c877c7293514343a2cca27ea237c73e2186e3a33db6 | 1 | 1 | [
"Compound::DB01069",
"Compound::DB00564"
] | [
"7a9ae9a56755a1ae7d1bdacc29de708161d737f026fa2fde41b59a4c96f75fb4"
] | [
{
"edge_id": "7a9ae9a56755a1ae7d1bdacc29de708161d737f026fa2fde41b59a4c96f75fb4",
"source_id": "Compound::DB01069",
"source_name": "Promethazine",
"relation_id": "Compound-resembles-Compound",
"target_id": "Compound::DB00564",
"target_name": "Carbamazepine"
}
] | [
"Compound::DB01069"
] | [
"Compound-resembles-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00564", "query_direction": "inverse", "structural_split_key": "9f76d60353e2bb00e4cc968caad9ad234303179144094333fc2f036c69974f41"} |
ff87490d884869392f40fdb65534253b68bc1f21ffc0a086eb9f270b1b51a2b5 | 12b82a4199f60015916970fde33d4fc6de15e09fd1e93d19b3e0986378e3f4db | [
{
"content": "According to the biomedical literature, Behcet's disease resembles which other disease?",
"role": "user"
},
{
"content": "Crohn's disease",
"role": "assistant"
}
] | atomic_qa | train | 33ee78e665a28c6e84a5e805e3a5de70a5ffb0993603e5517da97884b9bcfb08 | 1 | 1 | [
"Disease::DOID:13241",
"Disease::DOID:8778"
] | [
"8d3fae09eb19bfc70c9e1616226608048e350cefd461e427a457f56a5dafe1f9"
] | [
{
"edge_id": "8d3fae09eb19bfc70c9e1616226608048e350cefd461e427a457f56a5dafe1f9",
"source_id": "Disease::DOID:13241",
"source_name": "Behcet's disease",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:8778",
"target_name": "Crohn's disease"
}
] | [
"Disease::DOID:8778"
] | [
"Disease-resembles-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:13241", "query_direction": "forward", "structural_split_key": "50026c42fefd427483b895c96ceb60b56da9755b8e4d5208231f1bcaefb6e02c"} |
baf3e4a4e4b42869a3655de5a14af7c5f228c6ae07cd37246555b3fc5887c97f | 3e717df77859a63dbb1b8acf78cb06e1b6d2b913b80d838fb1b125cc47e69fa2 | [
{
"content": "Which compound helps relieve the symptoms of endogenous depression?",
"role": "user"
},
{
"content": "Sertraline",
"role": "assistant"
}
] | atomic_qa | train | 0dc8d79cf3f8ad777347ce3fb27966832e91dfe146a52b82d983734831f01752 | 1 | 1 | [
"Compound::DB01104",
"Disease::DOID:1595"
] | [
"473327adcd4ffd2d463851722e67d6cbc975af5238e42fcb66de3ccbbc84897c"
] | [
{
"edge_id": "473327adcd4ffd2d463851722e67d6cbc975af5238e42fcb66de3ccbbc84897c",
"source_id": "Compound::DB01104",
"source_name": "Sertraline",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:1595",
"target_name": "endogenous depression"
}
] | [
"Compound::DB01104"
] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 10} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:1595", "query_direction": "inverse", "structural_split_key": "86bccc1f90a292c3e4775ca6f3c2091e181d5570d945e81c641ed748a8387657"} |
26d299668b15b9fdccf2cdf1567980402451aebfee4887a455df407667fa512a | d199cda30e5ea4b83c4a33ea9f2773d66d9022a080a1b5774bde140172bd5b1f | [
{
"content": "Which gene does exposure to Bortezomib upregulate?",
"role": "user"
},
{
"content": "NR1H2",
"role": "assistant"
}
] | atomic_qa | train | 9b91507c367f0d401913a0207526d51221d04c0df88492f11c8cc1525517a4d5 | 1 | 1 | [
"Compound::DB00188",
"Gene::7376"
] | [
"dfb26fd040d5b243689de98b0538c99d5b5397f414527bcc378ef7c3397b747e"
] | [
{
"edge_id": "dfb26fd040d5b243689de98b0538c99d5b5397f414527bcc378ef7c3397b747e",
"source_id": "Compound::DB00188",
"source_name": "Bortezomib",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::7376",
"target_name": "NR1H2"
}
] | [
"Gene::7376"
] | [
"Compound-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 8} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00188", "query_direction": "forward", "structural_split_key": "21e1093aa5d0c7166aeb23529394c5b4982ae0b12a45a16f42bcbe05602f5bca"} |
1264f6a309bb26196270c8669274e192046a41431c15b44cba03eeb1251f13ad | 61a3e34479e9faca96a92aca2de3de4bf2bca26750f28e6f9a8dd40e07848769 | [
{
"content": "Which anatomy does rectum cancer affect or is related to?",
"role": "user"
},
{
"content": "lumbosacral nerve plexus",
"role": "assistant"
}
] | atomic_qa | train | 3eb7d609f1a136debf57e06e1ce55ae6b759dbf1d76c69d1fbb87183a1ba7e03 | 1 | 1 | [
"Disease::DOID:1993",
"Anatomy::UBERON:0001815"
] | [
"00cea8e61f25f675ecbd0dfeae0b4ab6bea4de047f022cb410b8894dd76e9a09"
] | [
{
"edge_id": "00cea8e61f25f675ecbd0dfeae0b4ab6bea4de047f022cb410b8894dd76e9a09",
"source_id": "Disease::DOID:1993",
"source_name": "rectum cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001815",
"target_name": "lumbosacral nerve plexus"
}
] | [
"Anatomy::UBERON:0001815"
] | [
"Disease-localizes-Anatomy"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:1993", "query_direction": "forward", "structural_split_key": "0a912f090dc064a568d88973da54076dee3eed26fffef67918a75cf13c9267c3"} |
4db0d74c2c7e6d539044e5a210d8935623c6ef997456b0fb17661ab93182b615 | 04f8a5fd7b9975e9a076ad0f17df1cf615ab3917fb1acc63dcebaa6af7f01e48 | [
{
"content": "In the biomedical literature, which disease is described as resembling membranous glomerulonephritis?",
"role": "user"
},
{
"content": "Hepatitis B",
"role": "assistant"
}
] | atomic_qa | train | 9e21e3ea617bf0ddbda765888804809e3a0672431482fa6d92a752948a582c7c | 1 | 1 | [
"Disease::DOID:2043",
"Disease::DOID:10976"
] | [
"6aa4579c9c99e5fad0b42b96d76a7ed9906a8d4141de40fd87a119ddefcfc68f"
] | [
{
"edge_id": "6aa4579c9c99e5fad0b42b96d76a7ed9906a8d4141de40fd87a119ddefcfc68f",
"source_id": "Disease::DOID:2043",
"source_name": "hepatitis B",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:10976",
"target_name": "membranous glomerulonephritis"
}
] | [
"Disease::DOID:2043"
] | [
"Disease-resembles-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:10976", "query_direction": "inverse", "structural_split_key": "edb9d2883d23fbae0b1eed9f96fa7453d902b1b994f0b6d60e90c2708193a1e1"} |
e30f64cca4eec2598de0db916861699d6231831c01d94d8dc655449c90b862f6 | 4703d73cddc5924a6ca495a743b32509c061ad12f4fd9015da90926ddc5e0a28 | [
{
"content": "According to the biomedical data, exposure to Simvastatin downregulates which gene?",
"role": "user"
},
{
"content": "CHAF1B",
"role": "assistant"
}
] | atomic_qa | train | 09aab9c152ac420251fbd01b9873c65689327ad597984c044b326aa71344f5dd | 1 | 1 | [
"Compound::DB00641",
"Gene::8208"
] | [
"07aa5f04439fcec47d4c6c1d9bd8be1179f80150adc766d1de3931a389c54e08"
] | [
{
"edge_id": "07aa5f04439fcec47d4c6c1d9bd8be1179f80150adc766d1de3931a389c54e08",
"source_id": "Compound::DB00641",
"source_name": "Simvastatin",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::8208",
"target_name": "CHAF1B"
}
] | [
"Gene::8208"
] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 12} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00641", "query_direction": "forward", "structural_split_key": "6b28ec02622e24dd77eb831c3d3ef77b5091d3d47e267effa8fd14ffb6bf0785"} |
c3fae23f1f4ab5a008f8c7cfb69b041fe3fb516de4f33cda4bd230ea80d03a7d | f4fac77fadabb17f3d4a71fc961ef14c88c330d7bb1121179bfed73bf9c0e9be | [
{
"content": "I'm looking into Chlordiazepoxide. Which disease does it help palliate symptoms for?",
"role": "user"
},
{
"content": "Alcohol dependence.",
"role": "assistant"
}
] | atomic_qa | train | 30a79a9f7ab71308479de8590b0f45273963aceea7620feb326114f105d28d9e | 1 | 1 | [
"Compound::DB00475",
"Disease::DOID:0050741"
] | [
"231776451e4bc85720cd01af7445c48bec7f1505e4c93cb3e35d68420c4e61b4"
] | [
{
"edge_id": "231776451e4bc85720cd01af7445c48bec7f1505e4c93cb3e35d68420c4e61b4",
"source_id": "Compound::DB00475",
"source_name": "Chlordiazepoxide",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:0050741",
"target_name": "alcohol dependence"
}
] | [
"Disease::DOID:0050741"
] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB00475", "query_direction": "forward", "structural_split_key": "009609b6a452139860f1a9691e2a1ff27c04bf51e1f6ac7ccfc95aeb655c3244"} |
b07db1b58818b229284a7e0b06ab21d177774ba94130c3c5759c627340ca47aa | bc7b5184defb9f78766b540d35f20699c31d9ba5763c55f80605f578c9b2defa | [
{
"content": "Which compound is included in the pharmacologic class of Organic Anion Transporting Polypeptide 1B1 Inhibitors?",
"role": "user"
},
{
"content": "Eltrombopag",
"role": "assistant"
}
] | atomic_qa | train | e476c4a7efeea76551b63263a12ca3c6f9b72b281d9e89e509970e16066ed63d | 1 | 1 | [
"Pharmacologic Class::N0000190107",
"Compound::DB06210"
] | [
"c7fdc2b14b9ced6ac9ebd4e61fd81a5135f2c76888fd5a8b0bce9749e6ff0ef3"
] | [
{
"edge_id": "c7fdc2b14b9ced6ac9ebd4e61fd81a5135f2c76888fd5a8b0bce9749e6ff0ef3",
"source_id": "Pharmacologic Class::N0000190107",
"source_name": "Organic Anion Transporting Polypeptide 1B1 Inhibitors",
"relation_id": "Pharmacologic Class-includes-Compound",
"target_id": "Compound::DB06210",
... | [
"Compound::DB06210"
] | [
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 16} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"DrugCentral",
"FDA via DrugCentral"
] | [
"CC BY 4.0",
"CC BY-NC 4.0"
] | {"known_id": "Pharmacologic Class::N0000190107", "query_direction": "forward", "structural_split_key": "6c445519fc9cb5561138fcd278400defc38b9f9ceaa8039a1779bc7b6de27b61"} |
9e1626436ef5ec2824591ad200138b91e64ef1fa899dab147be5915c780fe8ea | d9fbd92de1dc26bd379b7237ddb4f202bf65cc8a6e0e859461df9352890de81d | [
{
"content": "According to the data, IgA glomerulonephritis is associated with the downregulation of which gene?",
"role": "user"
},
{
"content": "NXT1",
"role": "assistant"
}
] | atomic_qa | train | 838a5b851559926b41b323326cbd5c587df45e27803976577beea833c0f5b993 | 1 | 1 | [
"Disease::DOID:2986",
"Gene::29107"
] | [
"64a725d6bd192624894e5a8ca6e2e936e679a7c0a949393a28b9feda0be6b26d"
] | [
{
"edge_id": "64a725d6bd192624894e5a8ca6e2e936e679a7c0a949393a28b9feda0be6b26d",
"source_id": "Disease::DOID:2986",
"source_name": "IgA glomerulonephritis",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::29107",
"target_name": "NXT1"
}
] | [
"Gene::29107"
] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:2986", "query_direction": "forward", "structural_split_key": "e517de21a73572a7a18710d803555a98ded74b540ba9d1583d8e29c721cde8c2"} |
66634996aebd1194b16ac0aa8e595e0b8b8ef47507899f2547ac1049bc1309c9 | aec874da9824efbfb29fb984d4a82d2a3694a24f659bb3e4edc5d989a076ba17 | [
{
"content": "Based on the provided biomedical database, which gene is linked to kidney cancer?\nA. TNFAIP6\nB. NUAK2\nC. TRIM74\nD. LMAN2L",
"role": "user"
},
{
"content": "D. LMAN2L",
"role": "assistant"
}
] | mcq | train | dbde4efe7fa2a018a672001c674006337b58f93d2078aa6e6a33d7830840ea8e | 1 | 1 | [
"Disease::DOID:263",
"Gene::81562"
] | [
"cc9a011432ddc8540bf30cb05cd43f43a27ff1f50cec08c340939ffca0ff1137"
] | [
{
"edge_id": "cc9a011432ddc8540bf30cb05cd43f43a27ff1f50cec08c340939ffca0ff1137",
"source_id": "Disease::DOID:263",
"source_name": "kidney cancer",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::81562",
"target_name": "LMAN2L"
}
] | [
"Gene::81562"
] | [
"Disease-associates-Gene"
] | mixed_hard_random | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 23} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"known_id": "Disease::DOID:263", "options": [["Gene::7130", "TNFAIP6"], ["Gene::81788", "NUAK2"], ["Gene::378108", "TRIM74"], ["Gene::81562", "LMAN2L"]], "query_direction": "forward", "structural_split_key": "4619a2eacdc3dd0d80ca3285d5ac3706c044664fb37c971f3d976d70fc3f2a6e"} |
a828d08b1def46670f574677cee32e5d75186a6ab0f56ba45454ee2108f3053a | 4087b2087f0fe75663936788c4f902daeead21af8998420c95068f4cb3037b33 | [
{
"content": "According to the provided biomedical data, the protein product of the GABRE gene is bound by which of the following compounds?\nA. Amiodarone\nB. Amlexanox\nC. Halazepam\nD. SIMEPREVIR",
"role": "user"
},
{
"content": "C",
"role": "assistant"
}
] | mcq | train | cfde8350198b41f93fe33c38333c1da8a268aa0bb28b5ac1c2a2f1e29063c00d | 1 | 1 | [
"Compound::DB00801",
"Gene::2564"
] | [
"5f1eb7279f181a16cc3ae528b69704c58f3609b0d7cbfdff63725c7044e05128"
] | [
{
"edge_id": "5f1eb7279f181a16cc3ae528b69704c58f3609b0d7cbfdff63725c7044e05128",
"source_id": "Compound::DB00801",
"source_name": "Halazepam",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::2564",
"target_name": "GABRE"
}
] | [
"Compound::DB00801"
] | [
"Compound-binds-Gene"
] | mixed_hard_random | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 30} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Gene::2564", "options": [["Compound::DB01118", "Amiodarone"], ["Compound::DB01025", "Amlexanox"], ["Compound::DB00801", "Halazepam"], ["Compound::DB06290", "SIMEPREVIR"]], "query_direction": "inverse", "structural_split_key": "3f88aaa9f29e343e4f3347fb4e796e257c3c5ee9e71690b0fc4e2604f44184c5"} |
a40ffa3b0e7538b5b85381460d81b177e0320c9c56701b88790bd73ca190e19b | cc1fedcce2e73929d08d9d83438eae3e8cca894c6b65ea0964fa1a02c92d4316 | [
{
"content": "I'm looking up information about Selegiline. According to the biomedical database, which of the following conditions does it help to palliate the symptoms of? Options are:\nA. chronic obstructive pulmonary disease\nB. fallopian tube cancer\nC. anemia\nD. Parkinson's disease",
"role": "user"
... | mcq | train | bad12f7e8bb276e20a4891575251344aaf95920c321f82376a96e0a71016db8c | 1 | 1 | [
"Compound::DB01037",
"Disease::DOID:14330"
] | [
"e64b89f81b3f5c2d31fd2f66db2ac24bbfd3648f8f78d4af7704f94c2410f4f1"
] | [
{
"edge_id": "e64b89f81b3f5c2d31fd2f66db2ac24bbfd3648f8f78d4af7704f94c2410f4f1",
"source_id": "Compound::DB01037",
"source_name": "Selegiline",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:14330",
"target_name": "Parkinson's disease"
}
] | [
"Disease::DOID:14330"
] | [
"Compound-palliates-Disease"
] | mixed_hard_random | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 43} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"known_id": "Compound::DB01037", "options": [["Disease::DOID:3083", "chronic obstructive pulmonary disease"], ["Disease::DOID:1964", "fallopian tube cancer"], ["Disease::DOID:2355", "anemia"], ["Disease::DOID:14330", "Parkinson's disease"]], "query_direction": "forward", "structural_split_key": "a8c6f0465bb74a1354cd43... |
1f09b650312ad35e7c56ff4d23350b97129311fdb0ff0594dbaf29ff19eef8d5 | 8dbf3a0a12c7d1d481af3d44e96d46965b7df380cbca954585e6550442a93781 | [
{
"content": "According to biomedical data, exposure to the chemotherapy drug Vinblastine is known to downregulate which of the following genes?\nA. CTTNBP2\nB. CACNA1A\nC. KAT6A\nD. MAX",
"role": "user"
},
{
"content": "C",
"role": "assistant"
}
] | mcq | train | f1ce179756824c527b1d41ae5d4930f874bf4fab511474731066776fcb399fc7 | 1 | 1 | [
"Compound::DB00570",
"Gene::7994"
] | [
"26301162abd322f77f712e2ca9928039819889a5ba411fb50f971e16d4ef421f"
] | [
{
"edge_id": "26301162abd322f77f712e2ca9928039819889a5ba411fb50f971e16d4ef421f",
"source_id": "Compound::DB00570",
"source_name": "Vinblastine",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::7994",
"target_name": "KAT6A"
}
] | [
"Gene::7994"
] | [
"Compound-downregulates-Gene"
] | mixed_hard_random | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 28} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Compound::DB00570", "options": [["Gene::83992", "CTTNBP2"], ["Gene::773", "CACNA1A"], ["Gene::7994", "KAT6A"], ["Gene::4149", "MAX"]], "query_direction": "forward", "structural_split_key": "a171a7e2a5de1ba435b334145493794d76458c98a930b9bae828b3b2de82c985"} |
786bf3f9a046ca61d7564e8db712e0f7eb07332aaf3b0cd68378e26275f28c33 | 8eecfaac03080da42c17ddaed3726a8dc1e5fa7f3bc752b05742c9fa70dd38be | [
{
"content": "Based on the available data, ureter cancer is most similar to which of these conditions?\n\nA. age related macular degeneration\nB. vaginal cancer\nC. degenerative disc disease\nD. germ cell cancer",
"role": "user"
},
{
"content": "B",
"role": "assistant"
}
] | mcq | train | a26a9a49889d94618242a2c1a32c4d16fffb464358f2c72784dc73bdd448f555 | 1 | 1 | [
"Disease::DOID:11819",
"Disease::DOID:119"
] | [
"52878f27befb730dc7938a5e4f2a6f5ebf443bc39148d9c83c31717ec6bc8515"
] | [
{
"edge_id": "52878f27befb730dc7938a5e4f2a6f5ebf443bc39148d9c83c31717ec6bc8515",
"source_id": "Disease::DOID:11819",
"source_name": "ureter cancer",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:119",
"target_name": "vaginal cancer"
}
] | [
"Disease::DOID:119"
] | [
"Disease-resembles-Disease"
] | mixed_hard_random | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 32} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"known_id": "Disease::DOID:11819", "options": [["Disease::DOID:10871", "age related macular degeneration"], ["Disease::DOID:119", "vaginal cancer"], ["Disease::DOID:90", "degenerative disc disease"], ["Disease::DOID:2994", "germ cell cancer"]], "query_direction": "forward", "structural_split_key": "7f8403dcebc9d9036e6... |
5d319ba79ef357144412d1536b23ee94c657987dbcd4806c8c7c901a1cda5375 | 90e8d9dddfb36fa4d1e1a2538d599c2c3e9448ad29499aeb7eeedb7506f9f9fc | [
{
"content": "I'm trying to find which compound is linked to the upregulation of HIST2H2BE. Based on the available data, which of these options would be the correct answer?\n\nA. Digitoxin\nB. Celecoxib\nC. Melphalan\nD. Sotalol",
"role": "user"
},
{
"content": "A",
"role": "assistant"
}
] | mcq | train | deb7bd64aee7775e63189dc9d2bc0e2ab089697c01630d4b9c39b72962b9d97e | 1 | 1 | [
"Compound::DB01396",
"Gene::8349"
] | [
"cb45c0b6905ccae7b0d4c7fe25ecc4d7788c461d199442917a8f61edd4b34080"
] | [
{
"edge_id": "cb45c0b6905ccae7b0d4c7fe25ecc4d7788c461d199442917a8f61edd4b34080",
"source_id": "Compound::DB01396",
"source_name": "Digitoxin",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::8349",
"target_name": "HIST2H2BE"
}
] | [
"Compound::DB01396"
] | [
"Compound-upregulates-Gene"
] | mixed_hard_random | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 36} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"known_id": "Gene::8349", "options": [["Compound::DB01396", "Digitoxin"], ["Compound::DB00482", "Celecoxib"], ["Compound::DB01042", "Melphalan"], ["Compound::DB00489", "Sotalol"]], "query_direction": "inverse", "structural_split_key": "689c84b8ea6e9a361f4a1d86c11a5093cf4a0e5927f8172e1c36637ad3295b4d"} |
d91e562bfadc8fb64ef976c1a5a1f2f5e54cc646094665989c4f486d67a84210 | 91e0f9bbc2456c18667d3c7e71c191ee071d60f777bb11cc611c8d960abd9a60 | [
{
"content": "Does the available information support the following claim? Fulvestrant is a disease-modifying treatment for breast cancer. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | f982d61fb9612caff77340ef69f2e08eb95b7944e83581c716a32d8f287c2e88 | 1 | 1 | [
"Compound::DB00947",
"Disease::DOID:1612"
] | [
"8c6f126dadd865328a6307b1b61c02ea5c6dd2952301b748619f3d915ee119e3"
] | [
{
"edge_id": "8c6f126dadd865328a6307b1b61c02ea5c6dd2952301b748619f3d915ee119e3",
"source_id": "Compound::DB00947",
"source_name": "Fulvestrant",
"relation_id": "Compound-treats-Disease",
"target_id": "Disease::DOID:1612",
"target_name": "breast cancer"
}
] | [
"Disease::DOID:1612"
] | [
"Compound-treats-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 31} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"claim_source_id": "Compound::DB00947", "claim_source_name": "Fulvestrant", "claim_target_id": "Disease::DOID:1612", "claim_target_name": "breast cancer", "is_positive": true, "query_direction": "forward", "structural_split_key": "25264fbcc8557a882ee5992acf28b3d74e8ce18a9b9a3efd0bb8b817c383c019"} |
10349afdc4fc0418cc93f7697b8fd0fb784b4aea0581eb1288d2a407581cf16c | eae3f6dded3c5bf56f3469400451b57660622676332c0f4b7b39d9628c61f692 | [
{
"content": "Does the available information support the following claim? thyroid cancer resembles bone cancer. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | c2107267b6ad35df0a40b5095aa1598a05f0ec06524cecdfd9615ea787f74f59 | 1 | 1 | [
"Disease::DOID:184",
"Disease::DOID:1781"
] | [
"fbef4cdcec9ec8ef9a7303d0779e6138c2faacbc837745878a48f89d8f4c55cd"
] | [
{
"edge_id": "fbef4cdcec9ec8ef9a7303d0779e6138c2faacbc837745878a48f89d8f4c55cd",
"source_id": "Disease::DOID:184",
"source_name": "bone cancer",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:1781",
"target_name": "thyroid cancer"
}
] | [
"Disease::DOID:184"
] | [
"Disease-resembles-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 28} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"claim_source_id": "Disease::DOID:184", "claim_source_name": "bone cancer", "claim_target_id": "Disease::DOID:1781", "claim_target_name": "thyroid cancer", "is_positive": true, "query_direction": "inverse", "structural_split_key": "8a99bdb765b36b8c7fb2065f22fa7662b5d7b02445588fa0eca04fce3e43b4ea"} |
b584b56f5f3fba1a67a3a3a69ef064af444df1b34acea6149c055fb56540bfbb | 77e77eeab17128b362dfb1ba7f1e954656725a7e0131a7b6775c293af5bdd260 | [
{
"content": "Does the available information support the following claim? Symptoms of chronic obstructive pulmonary disease are palliated by Ofloxacin. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assista... | support_classification | train | 0ab5bc44c270cd76810ba7f5fcf8362d1fd3edbb6bc4cdb09e2923a26ec21a59 | 1 | 1 | [
"Compound::DB01165",
"Disease::DOID:3083"
] | [
"f1f3c8dfed5860851662a05bab4a67f67b02d110b5db5964f6f6d965221826b2"
] | [
{
"edge_id": "f1f3c8dfed5860851662a05bab4a67f67b02d110b5db5964f6f6d965221826b2",
"source_id": "Compound::DB01165",
"source_name": "Ofloxacin",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:3083",
"target_name": "chronic obstructive pulmonary disease"
}
] | [
"Compound::DB01165"
] | [
"Compound-palliates-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 33} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"claim_source_id": "Compound::DB01165", "claim_source_name": "Ofloxacin", "claim_target_id": "Disease::DOID:3083", "claim_target_name": "chronic obstructive pulmonary disease", "is_positive": true, "query_direction": "inverse", "structural_split_key": "4d70f8736755ba26770a4bcdf49e934efe0d14346fd0acb1ba08dc7a72e53ea1"} |
48c0d10947873a385a7344af9fdeb5f30b64de67ef53383cd054fdcd6d2d365a | cd9080403d9d3618f36bde7a4f2432b544373100c577fdaa1d7d0bcee463a92b | [
{
"content": "Does the available information support the following claim? lung cancer can present with Breakthrough Pain. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | a2b4430bc19aa1f6bd90940085302c8584ae1a795eb2e147870077b4fdaab1da | 1 | 1 | [
"Disease::DOID:1324",
"Symptom::D059390"
] | [
"56343ad3fc464a1bcdc52d2062398ed445a17dd7b0897f4c068baca4f3bb8d04"
] | [
{
"edge_id": "56343ad3fc464a1bcdc52d2062398ed445a17dd7b0897f4c068baca4f3bb8d04",
"source_id": "Disease::DOID:1324",
"source_name": "lung cancer",
"relation_id": "Disease-presents-Symptom",
"target_id": "Symptom::D059390",
"target_name": "Breakthrough Pain"
}
] | [
"Symptom::D059390"
] | [
"Disease-presents-Symptom"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 30} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"MeSH"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"claim_source_id": "Disease::DOID:1324", "claim_source_name": "lung cancer", "claim_target_id": "Symptom::D059390", "claim_target_name": "Breakthrough Pain", "is_positive": true, "query_direction": "forward", "structural_split_key": "996ca0be6039325b2dc45460a024f6ffd3ce658f5888e79394c5c9543e5ac4a9"} |
a91c1936ee634a3588baa977f4a2d63ded94f93eedd363126bae9e7d8c4bc7f4 | 33717683ff32c4c85b86dbc0411c431926ab846f7f82a43b263949e742b918bd | [
{
"content": "Does the available information support the following claim? Symptoms of Parkinson's disease are palliated by Diphenhydramine. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | 12d3783dc309a786f66ad9c55477b93d9f011a29684115441843f10452e6e314 | 1 | 1 | [
"Compound::DB01075",
"Disease::DOID:14330"
] | [
"72a0a971c9962dc37836e4ed718d35ee4a69fd838d08ee74acd534e5c716239b"
] | [
{
"edge_id": "72a0a971c9962dc37836e4ed718d35ee4a69fd838d08ee74acd534e5c716239b",
"source_id": "Compound::DB01075",
"source_name": "Diphenhydramine",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:14330",
"target_name": "Parkinson's disease"
}
] | [
"Compound::DB01075"
] | [
"Compound-palliates-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 31} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"claim_source_id": "Compound::DB01075", "claim_source_name": "Diphenhydramine", "claim_target_id": "Disease::DOID:14330", "claim_target_name": "Parkinson's disease", "is_positive": true, "query_direction": "inverse", "structural_split_key": "399f36075f60c475f663c86df5ab7e384862c75a3587eb45d332f50520c55c52"} |
0ade98f4321d986bcc5c97562f2fc4f8dd873fe05a6e6fdf2c3011be645786e3 | ec526fa692adf97db048e19f5a5486484230cad0e2e25d10cfa4c8920c2d9a6d | [
{
"content": "Does the available information support the following claim? colon cancer affects or is related to perineum. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | f7a9fc8ed52610393accbd5f8dc09e7d07fec2cfb92da31cad2fac7834f8f3bb | 1 | 1 | [
"Disease::DOID:219",
"Anatomy::UBERON:0002356"
] | [
"540b80af0e38b0c736f32a7a6f3d9d943f7accf59c7df560bddc008898a259ba"
] | [
{
"edge_id": "540b80af0e38b0c736f32a7a6f3d9d943f7accf59c7df560bddc008898a259ba",
"source_id": "Disease::DOID:219",
"source_name": "colon cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0002356",
"target_name": "perineum"
}
] | [
"Anatomy::UBERON:0002356"
] | [
"Disease-localizes-Anatomy"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 31} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"claim_source_id": "Disease::DOID:219", "claim_source_name": "colon cancer", "claim_target_id": "Anatomy::UBERON:0002356", "claim_target_name": "perineum", "is_positive": true, "query_direction": "forward", "structural_split_key": "0ff06b9860e1dd2027b9d2d144107a5048fd6694c9f51c1bdbba02e19fa0de92"} |
f178bbf43ed1aaaf4ec6d48d0cb579a82d2d8191da3090d9577264b05e6c2866 | 074f93aba4bf59de620a308b3f49bfbe99e0586c08d9d008ac50627acbdd4583 | [
{
"content": "Does the available information support the claim that vitiligo resembles psoriasis? Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | d541b6bc7eb9e7e5761d358bf8eebf3b74387aadb141fdb8cef1776aa1e809e3 | 1 | 1 | [
"Disease::DOID:8893",
"Disease::DOID:12306"
] | [
"c1871a79774a3c93947052a5d0689887884a3a530762f91b81791c8a545f483f"
] | [
{
"edge_id": "c1871a79774a3c93947052a5d0689887884a3a530762f91b81791c8a545f483f",
"source_id": "Disease::DOID:8893",
"source_name": "psoriasis",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:12306",
"target_name": "vitiligo"
}
] | [
"Disease::DOID:8893"
] | [
"Disease-resembles-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 26} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"claim_source_id": "Disease::DOID:8893", "claim_source_name": "psoriasis", "claim_target_id": "Disease::DOID:12306", "claim_target_name": "vitiligo", "is_positive": true, "query_direction": "inverse", "structural_split_key": "20a32269de2aa524b408706e0e4569a57fe6c4877ea14eb97a2ff0fb940aa2c6"} |
e2a92732da91790a029a8a9cb0718f3a78a768236ff3b94dc75e35c6b934ce3c | d29f8adf85d79e7e1a827cef95667f7cdc4f1e591e85057925bdfba58c882b26 | [
{
"content": "Does the available information support the following claim? CLPP is downregulated in samples exposed to Everolimus. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | 24504024b5d182eb8f87a3afc5e2b05efa089dd3194731098fdbcf6652f9d9c7 | 1 | 1 | [
"Compound::DB01590",
"Gene::8192"
] | [
"d55980923890772752da1e7466fd6cfad11260f4ab7524606d372e21ca3d8a15"
] | [
{
"edge_id": "d55980923890772752da1e7466fd6cfad11260f4ab7524606d372e21ca3d8a15",
"source_id": "Compound::DB01590",
"source_name": "Everolimus",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::8192",
"target_name": "CLPP"
}
] | [
"Compound::DB01590"
] | [
"Compound-downregulates-Gene"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 31} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"claim_source_id": "Compound::DB01590", "claim_source_name": "Everolimus", "claim_target_id": "Gene::8192", "claim_target_name": "CLPP", "is_positive": true, "query_direction": "inverse", "structural_split_key": "abfc81171748731ead61b219c0fdaa26632053a96755d943e606fa00cb989ae1"} |
9523029dcd3a722ac4cb3e713481b5f0d7f0497567870ea1bdc57d77aeb26ce7 | 1ab1f6388240480699306d222b8dab46ca89f8adc68a25704ac70b84854f6b30 | [
{
"content": "Does the available information support the following claim? Vinorelbine is a disease-modifying treatment for hematologic cancer. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | c49ded6ffe53dd9b1835ac292028bce6632b64106929ca26367be95ea972afc5 | 1 | 1 | [
"Compound::DB00361",
"Disease::DOID:2531"
] | [
"d9fc8c2474ce41918daa412a9eacd975a35c4b2ed1597592569ccdb7fe613642"
] | [
{
"edge_id": "d9fc8c2474ce41918daa412a9eacd975a35c4b2ed1597592569ccdb7fe613642",
"source_id": "Compound::DB00361",
"source_name": "Vinorelbine",
"relation_id": "Compound-treats-Disease",
"target_id": "Disease::DOID:2531",
"target_name": "hematologic cancer"
}
] | [
"Disease::DOID:2531"
] | [
"Compound-treats-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 31} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"claim_source_id": "Compound::DB00361", "claim_source_name": "Vinorelbine", "claim_target_id": "Disease::DOID:2531", "claim_target_name": "hematologic cancer", "is_positive": true, "query_direction": "forward", "structural_split_key": "c4a4f8f3d4bcba77e56742aa9f63a810e0eb6123a5cecd21422ddbb5b270d8e1"} |
6f5bc4a2af8832ef589884d1434413b9ed8b5319ebb0721f8195028381db70f8 | 26d5f50153bfe6d7236a276f9a7fbb4c9dc391bdebf851691f47bec9b8736381 | [
{
"content": "Does the available information support the following claim? metabolic syndrome X is treated with the disease-modifying compound Metformin. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assist... | support_classification | train | 09910145391615fd7fcc01a7a729fb07ff8a26f81bae6d39ac6514bae9617bd7 | 1 | 1 | [
"Compound::DB00331",
"Disease::DOID:14221"
] | [
"f048aac6aea4a8cf0a9bbb7ae32416f375ca9035a3f3f0c43f213c3f8cbb21f1"
] | [
{
"edge_id": "f048aac6aea4a8cf0a9bbb7ae32416f375ca9035a3f3f0c43f213c3f8cbb21f1",
"source_id": "Compound::DB00331",
"source_name": "Metformin",
"relation_id": "Compound-treats-Disease",
"target_id": "Disease::DOID:14221",
"target_name": "metabolic syndrome X"
}
] | [
"Compound::DB00331"
] | [
"Compound-treats-Disease"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 33} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"claim_source_id": "Compound::DB00331", "claim_source_name": "Metformin", "claim_target_id": "Disease::DOID:14221", "claim_target_name": "metabolic syndrome X", "is_positive": true, "query_direction": "inverse", "structural_split_key": "01057a0f2802b9dd50b8bad8c22131fa3d57ee84d8555164f33229d6eee9db44"} |
558c143b54527e738ff6d4f2ef9451fa2100957b0fa84ae6c122f5c62ab01959 | 85207bf7d40da9bc1f53b0e89d54d0b1a916c0ef30f7dd5be97c78d59f1598ba | [
{
"content": "Does the available information support the following claim? dilated cardiomyopathy is associated with FASLG. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | 2d21ade652486ecf6e9d1cb716ef008dfcc8bac76cada2fa6ccb936b5e128bf2 | 1 | 1 | [
"Disease::DOID:12930",
"Gene::356"
] | [
"43e1ee576d7021181a7309ce88b4a2769c80fda8df7d14c378df0fd11739c814"
] | [
{
"edge_id": "43e1ee576d7021181a7309ce88b4a2769c80fda8df7d14c378df0fd11739c814",
"source_id": "Disease::DOID:12930",
"source_name": "dilated cardiomyopathy",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::356",
"target_name": "FASLG"
}
] | [
"Gene::356"
] | [
"Disease-associates-Gene"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 29} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC0 1.0",
"ODbL 1.0"
] | {"claim_source_id": "Disease::DOID:12930", "claim_source_name": "dilated cardiomyopathy", "claim_target_id": "Gene::356", "claim_target_name": "FASLG", "is_positive": true, "query_direction": "forward", "structural_split_key": "17e46cffb397d28bb339b843b7a06636a1e8bac44249a4f5814d65f223218de5"} |
8c0c6712e58f0ed0f917d667ccfea21b93a21885c37cd9fe4712c05531293aa5 | e915ef97f1a8feefaaa9aa8e4b47fd498cba31b07a04eb738e62224e4088e780 | [
{
"content": "Does the available information support the following claim? The protein product of CYP2E1 is bound by Etoricoxib. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | a6ee9226061432fb6077cdb19772400a8964c122795e55b6f0ad73ec3b894da9 | 1 | 1 | [
"Compound::DB01628",
"Gene::1571"
] | [
"8f06b4cbd87ba890964b1361fe433be3d65521be455166ec21943af1134a847e"
] | [
{
"edge_id": "8f06b4cbd87ba890964b1361fe433be3d65521be455166ec21943af1134a847e",
"source_id": "Compound::DB01628",
"source_name": "Etoricoxib",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::1571",
"target_name": "CYP2E1"
}
] | [
"Compound::DB01628"
] | [
"Compound-binds-Gene"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 32} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"claim_source_id": "Compound::DB01628", "claim_source_name": "Etoricoxib", "claim_target_id": "Gene::1571", "claim_target_name": "CYP2E1", "is_positive": true, "query_direction": "inverse", "structural_split_key": "f52c98dd00a8b97b7c93ac4965221702931832bc31ce1aab135c1ffac884d86b"} |
55c855f312c965c4be26dc317a995b176976b47cfa02a229f8388e2601522a2e | 83e41e4f9616c25f0d197a180ead4586b53c61fb125dba58d06634e52ce7cbf8 | [
{
"content": "Does the available information support the claim that rheumatoid arthritis upregulates NLK? Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | aea108c9147da44df3a244316c104ef0d96df2f4816d159f7eca6b949f1ced1a | 1 | 1 | [
"Disease::DOID:7148",
"Gene::51701"
] | [
"e9f19ad5836abaaf3528848068e9e3175cf598edfa544be49f023312091cffc1"
] | [
{
"edge_id": "e9f19ad5836abaaf3528848068e9e3175cf598edfa544be49f023312091cffc1",
"source_id": "Disease::DOID:7148",
"source_name": "rheumatoid arthritis",
"relation_id": "Disease-upregulates-Gene",
"target_id": "Gene::51701",
"target_name": "NLK"
}
] | [
"Gene::51701"
] | [
"Disease-upregulates-Gene"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 27} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"claim_source_id": "Disease::DOID:7148", "claim_source_name": "rheumatoid arthritis", "claim_target_id": "Gene::51701", "claim_target_name": "NLK", "is_positive": true, "query_direction": "forward", "structural_split_key": "ccaf41b30460ba047352a0036092fda710ab58c594a8ebe53a75b491259bf9d5"} |
bee4a33212ae2f3cec9c3670ad1780de3990e69fe2009d29bc22ec485ae1db18 | 080c5abc06a356e07e112a8bbcb0e67191e9ec0aae3b88b400b8c440f7d10bd9 | [
{
"content": "Does the available information support the following claim? ovarian cancer downregulates AKAP8. Answer yes or no.",
"role": "user"
},
{
"content": "Yes, according to the information I have, this relationship is supported.",
"role": "assistant"
}
] | support_classification | train | 5044a6e2fe275b0a5649b4b01162d0a30363005843a79e0e59059ff23fd43694 | 1 | 1 | [
"Disease::DOID:2394",
"Gene::10270"
] | [
"b34bda5caafbfa5702af5129c983f5cdffe142b4a1f88b8c1f4d2d5541b8e100"
] | [
{
"edge_id": "b34bda5caafbfa5702af5129c983f5cdffe142b4a1f88b8c1f4d2d5541b8e100",
"source_id": "Disease::DOID:2394",
"source_name": "ovarian cancer",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::10270",
"target_name": "AKAP8"
}
] | [
"Gene::10270"
] | [
"Disease-downregulates-Gene"
] | positive | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 27} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"claim_source_id": "Disease::DOID:2394", "claim_source_name": "ovarian cancer", "claim_target_id": "Gene::10270", "claim_target_name": "AKAP8", "is_positive": true, "query_direction": "forward", "structural_split_key": "d919c74ab63ee8105e535c9f23e4055d18ffb916f10ee664f107caac5b6dd612"} |
1732c769f2b92aed316aefeae346c33f548cb5a9c96bd53d8479ea5d802afc7b | a27362d462c5a180d1a1c3e7323ebf603b9510d36c35c28b7c2648079a3cd007 | [
{
"content": "I'm looking into the connection between Nonoxynol-9 and the CHERP gene. According to the data, how are these two related?",
"role": "user"
},
{
"content": "Exposure to Nonoxynol-9 downregulates the CHERP gene.",
"role": "assistant"
}
] | relation_classification | train | cef8807e67baedffda016475a18a9f319de20247ead904c73d4071b634f85e35 | 1 | 1 | [
"Compound::DB06804",
"Gene::10523"
] | [
"638718d183db9fcdc3c0e6fbb8e3f737e52cf03f8402f3257495ff37934e2e1f"
] | [
{
"edge_id": "638718d183db9fcdc3c0e6fbb8e3f737e52cf03f8402f3257495ff37934e2e1f",
"source_id": "Compound::DB06804",
"source_name": "Nonoxynol-9",
"relation_id": "Compound-downregulates-Gene",
"target_id": "Gene::10523",
"target_name": "CHERP"
}
] | [] | [
"Compound-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 27} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000"
] | [
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"pair_node_ids": ["Compound::DB06804", "Gene::10523"], "structural_split_key": "44db217775191abaccfe61331464c58d87ed8c0a7a6112e49486236ed9603ea6"} |
acee40110d62d5c4891c21d4d9a7316a79142d18657ca4caf82a89025ffc00ac | 9ab7d76eb2ead339b95eaed27d3cf4104a9a67dca85a30a1e80530882caeb410 | [
{
"content": "How are Aprepitant and Cytochrome P450 2C9 Inducers connected?",
"role": "user"
},
{
"content": "Aprepitant belongs to the pharmacologic class Cytochrome P450 2C9 Inducers.",
"role": "assistant"
}
] | relation_classification | train | dfc08e82a079e40935b466a3c3ce0455f12595a97921a4515e09929549b9e93c | 1 | 1 | [
"Pharmacologic Class::N0000185507",
"Compound::DB00673"
] | [
"b7ddf27f27d61577fadc34b67eba777deb9a5c881996efd6dd37408ae7ee216e"
] | [
{
"edge_id": "b7ddf27f27d61577fadc34b67eba777deb9a5c881996efd6dd37408ae7ee216e",
"source_id": "Pharmacologic Class::N0000185507",
"source_name": "Cytochrome P450 2C9 Inducers",
"relation_id": "Pharmacologic Class-includes-Compound",
"target_id": "Compound::DB00673",
"target_name": "Aprepitan... | [] | [
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"DrugCentral",
"FDA via DrugCentral"
] | [
"CC BY 4.0",
"CC BY-NC 4.0"
] | {"pair_node_ids": ["Compound::DB00673", "Pharmacologic Class::N0000185507"], "structural_split_key": "faf6d6c514e29b9c171d978ae2bc125ec6793e0b8866d22133ef11c10bb0fbfc"} |
d1357bc0e505817c6945a42b0835d10d51263ab5bb088a83860b42d160f65045 | 7986750844fbc903a8d2571308d9cecf8cec1afec3a126f126777b6ed6c2d811 | [
{
"content": "Can you tell me how Crohn's disease is connected to Purpura, Schoenlein-Henoch?",
"role": "user"
},
{
"content": "Crohn's disease can present with Purpura, Schoenlein-Henoch.",
"role": "assistant"
}
] | relation_classification | train | 9862ea863ac339b975e0f071e0f5a7c922689088932a86393b6825745f8ff6a9 | 1 | 1 | [
"Disease::DOID:8778",
"Symptom::D011695"
] | [
"59c88da3490d1e5d1cf6cadfee40feb33eabfae42a92929716a33f7a18541afe"
] | [
{
"edge_id": "59c88da3490d1e5d1cf6cadfee40feb33eabfae42a92929716a33f7a18541afe",
"source_id": "Disease::DOID:8778",
"source_name": "Crohn's disease",
"relation_id": "Disease-presents-Symptom",
"target_id": "Symptom::D011695",
"target_name": "Purpura, Schoenlein-Henoch"
}
] | [] | [
"Disease-presents-Symptom"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence",
"MeSH"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"pair_node_ids": ["Disease::DOID:8778", "Symptom::D011695"], "structural_split_key": "8ea10d37b6159a9c62f5d78023f660f7a4f42f5ef37edda26f85b7c08198877a"} |
189ed4e8787c093b5dc6ccd96e8d4efb6d07438096f4a7a350497f1203cf1ef3 | 644be3c09269d3e91278b07e84407e923402335ec1505faea291dc3feee43f0e | [
{
"content": "What is the connection between Alzheimer's disease and the DONSON gene?",
"role": "user"
},
{
"content": "Alzheimer's disease upregulates DONSON.",
"role": "assistant"
}
] | relation_classification | train | 99c345df91aae9cc0ddfc5a7b70a80bc160b03dc1b6eb3b8c8aa17d670f30488 | 1 | 1 | [
"Disease::DOID:10652",
"Gene::29980"
] | [
"ef467a8a2356f30db979706ace6001cadf05dabdcfa2c6cb1ca39c5444f9603b"
] | [
{
"edge_id": "ef467a8a2356f30db979706ace6001cadf05dabdcfa2c6cb1ca39c5444f9603b",
"source_id": "Disease::DOID:10652",
"source_name": "Alzheimer's disease",
"relation_id": "Disease-upregulates-Gene",
"target_id": "Gene::29980",
"target_name": "DONSON"
}
] | [] | [
"Disease-upregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 15} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"pair_node_ids": ["Disease::DOID:10652", "Gene::29980"], "structural_split_key": "8216e7343c18a1a8a6a4db8fb89cfe37513793738421a6aa8ebad0ca48d500e3"} |
03f61deb4ecb53c5f296764bbe576de60b0e49ed76b367cd6ce1ba7bcdb08522 | e6944734bf0bf55063f62763f8c3601b654066a4c6e1d340b45dfec56a6b8761 | [
{
"content": "How are breast cancer and SORBS1 connected? What is the specific relationship between this disease and the gene?",
"role": "user"
},
{
"content": "Breast cancer downregulates SORBS1, meaning the gene is under-expressed in disease samples.",
"role": "assistant"
}
] | relation_classification | train | cc1da128fd68340d0697f77f4236d3862a058fd2220026888e59ee0c8092cdd5 | 1 | 1 | [
"Disease::DOID:1612",
"Gene::10580"
] | [
"4b0d2ee78d2c9dc85fff17ef67216e3411650e13e9b7a109d0d6da44b9fbcf91"
] | [
{
"edge_id": "4b0d2ee78d2c9dc85fff17ef67216e3411650e13e9b7a109d0d6da44b9fbcf91",
"source_id": "Disease::DOID:1612",
"source_name": "breast cancer",
"relation_id": "Disease-downregulates-Gene",
"target_id": "Gene::10580",
"target_name": "SORBS1"
}
] | [] | [
"Disease-downregulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 30} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"STARGEO"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"pair_node_ids": ["Disease::DOID:1612", "Gene::10580"], "structural_split_key": "633f068930854e495ef92b36b5d5712478837069f2943ac85fe771e111ff234d"} |
1ab5c3c10475749054c1bc602607b8af655e4eac3be5a013e2834451d4994950 | 98b7f542b78b144d2aeaf639d4c97f3e8ad492abb74b761bcf66b66953567366 | [
{
"content": "I'm researching Brompheniramine and its potential targets. What is the specific interaction between Brompheniramine and the CHRM2 protein?",
"role": "user"
},
{
"content": "Based on the available biomedical data, Brompheniramine binds to the protein product of CHRM2.",
"role": "ass... | relation_classification | train | 0adb10a293ea3c034a816a86c5f961640e5cbc06c06cb941030aa526ad5f450d | 1 | 1 | [
"Compound::DB00835",
"Gene::1129"
] | [
"1438becd02db2b6c782f02752317b87782839e6bb82f3c1d98aeb7269654a8ab"
] | [
{
"edge_id": "1438becd02db2b6c782f02752317b87782839e6bb82f3c1d98aeb7269654a8ab",
"source_id": "Compound::DB00835",
"source_name": "Brompheniramine",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::1129",
"target_name": "CHRM2"
}
] | [] | [
"Compound-binds-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 32} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY-NC 4.0",
"CC0 1.0"
] | {"pair_node_ids": ["Compound::DB00835", "Gene::1129"], "structural_split_key": "ba930f175feabaccf3fe5426a40876b48671e603615830c2aed03b9a13d096bb"} |
dcb1ff89cad164369489318148adb997534bcc9873b5603d3915c00cbad802bf | fa7ab4ab935d34ec2a2ea9408b90fdf240f5c34a15bc9fdcc1ddf1d05225cfdc | [
{
"content": "What is the connection between vulva cancer and uterine fibroid?",
"role": "user"
},
{
"content": "According to the data, uterine fibroid resembles vulva cancer.",
"role": "assistant"
}
] | relation_classification | train | e61bd580e744c66f1a4da9207d60f29951d5393591db843243e9516714b9e343 | 1 | 1 | [
"Disease::DOID:13223",
"Disease::DOID:1245"
] | [
"ac9f5e1e7bb9d4facef488e9e70b2f73062021dde5fd26ea0fbc4d9032b5c34c"
] | [
{
"edge_id": "ac9f5e1e7bb9d4facef488e9e70b2f73062021dde5fd26ea0fbc4d9032b5c34c",
"source_id": "Disease::DOID:13223",
"source_name": "uterine fibroid",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:1245",
"target_name": "vulva cancer"
}
] | [] | [
"Disease-resembles-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 19} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"pair_node_ids": ["Disease::DOID:1245", "Disease::DOID:13223"], "structural_split_key": "dde0b358b2efa1a8b17577bdf4715c235f7929f6b7b7f0ae04f6c2645350383f"} |
fb2d5e30b245c588157e700447cc7bc5a6eef882577d8123a24477fbfaddbec3 | a2df1fc62e5e76a967f71e8d2844495af50150ae271af6d5acc9bb888583623b | [
{
"content": "I'm looking into the connection between lidocaine and rheumatoid arthritis. What's the relationship between these two?",
"role": "user"
},
{
"content": "Lidocaine palliates symptoms of rheumatoid arthritis.",
"role": "assistant"
}
] | relation_classification | train | a109c25de97a62c94c0ef894233d9dc01906f28d2daa0f12b8cf9ce70f2a5931 | 1 | 1 | [
"Compound::DB00281",
"Disease::DOID:7148"
] | [
"11c8c65bc6dc92c8b997b833ce69b69baad88b23719640481fdf3416ca0bf90e"
] | [
{
"edge_id": "11c8c65bc6dc92c8b997b833ce69b69baad88b23719640481fdf3416ca0bf90e",
"source_id": "Compound::DB00281",
"source_name": "Lidocaine",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:7148",
"target_name": "rheumatoid arthritis"
}
] | [] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 22} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"pair_node_ids": ["Compound::DB00281", "Disease::DOID:7148"], "structural_split_key": "8218a94b2b70bd2a871fd68d9126d39c9165176758bcc47a8e0e18bc4f07a9d7"} |
b6fe5874b6431e39368a245c823554db76034034272912edbbf684858c864865 | 934e536a002ca06b18538a8a0ffc3f4975017a5f582824483cbb9a81012fa11e | [
{
"content": "What's the connection between Clonazepam and bipolar disorder?",
"role": "user"
},
{
"content": "Clonazepam palliates symptoms of bipolar disorder.",
"role": "assistant"
}
] | relation_classification | train | b8eac46b65eee367eb83abf1057d3c06257cf44aab3901abd95534e35ab9c147 | 1 | 1 | [
"Compound::DB01068",
"Disease::DOID:3312"
] | [
"c916b89e4595d8f48c3202daab1faeba946b9a250d704aafbfff3f623534f113"
] | [
{
"edge_id": "c916b89e4595d8f48c3202daab1faeba946b9a250d704aafbfff3f623534f113",
"source_id": "Compound::DB01068",
"source_name": "Clonazepam",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:3312",
"target_name": "bipolar disorder"
}
] | [] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 14} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"pair_node_ids": ["Compound::DB01068", "Disease::DOID:3312"], "structural_split_key": "b776445ea6de86862b4028624c9f9a1af3bce786c7bddcc2e65c539338f52440"} |
e4478058810e9251b3d42495ed3e58a9a63d769c381b03046ae517d9cd5f88f9 | 70ff23b7dcfc05adb5d58342cc410b956a0fbd06fcda45bea63ca2ecdda7e740 | [
{
"content": "I'm trying to understand the connection between Dextromethorphan and multiple sclerosis. What relationship do they have?",
"role": "user"
},
{
"content": "Dextromethorphan palliates symptoms of multiple sclerosis.",
"role": "assistant"
}
] | relation_classification | train | 9bcde7c00dde7a8ef4b0fd9f070e6eea761b363e7da14675c16c7e63df9de483 | 1 | 1 | [
"Compound::DB00514",
"Disease::DOID:2377"
] | [
"59683b226486bd18445c52a41acb13748ca1cf068b42ff786a12f7f1ec73754e"
] | [
{
"edge_id": "59683b226486bd18445c52a41acb13748ca1cf068b42ff786a12f7f1ec73754e",
"source_id": "Compound::DB00514",
"source_name": "Dextromethorphan",
"relation_id": "Compound-palliates-Disease",
"target_id": "Disease::DOID:2377",
"target_name": "multiple sclerosis"
}
] | [] | [
"Compound-palliates-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 22} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"pair_node_ids": ["Compound::DB00514", "Disease::DOID:2377"], "structural_split_key": "18049a55c5e752061402d70c4a9e9a1670ab3b0e6c3041821b572c1b8d5ba448"} |
fa3a3394366249146d8244b9126a88bd4b1061699be75b6c99fa25c7bc7709b3 | 0fd046c7e594eae039020a0e14d0bfa4a7638a00dbd58d69dc50c40f732d8800 | [
{
"content": "I'm looking into the connection between Paclitaxel and lung cancer. How are they related according to the available biomedical data?",
"role": "user"
},
{
"content": "Paclitaxel is a disease-modifying treatment for lung cancer.",
"role": "assistant"
}
] | relation_classification | train | 59e58b63e3832d31f85e978e925ebd841cfa2832dd81ed9790b0f1c052dd8fbc | 1 | 1 | [
"Compound::DB01229",
"Disease::DOID:1324"
] | [
"eb14817845ddb3513a4aeb0b8c06bf0274a9f0f4b6e1e597c5ba7afe4157c1f3"
] | [
{
"edge_id": "eb14817845ddb3513a4aeb0b8c06bf0274a9f0f4b6e1e597c5ba7afe4157c1f3",
"source_id": "Compound::DB01229",
"source_name": "Paclitaxel",
"relation_id": "Compound-treats-Disease",
"target_id": "Disease::DOID:1324",
"target_name": "lung cancer"
}
] | [] | [
"Compound-treats-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 28} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"pair_node_ids": ["Compound::DB01229", "Disease::DOID:1324"], "structural_split_key": "e1d935b2752299db53aa9093672e235ce6ed5b9b4e630cfe550e26e5df1e02a8"} |
cb7bb23306ecaf8e358e634c7b68bd1990e5682e2491b3e7308acc924f85bef9 | 420c412204ac805edf18939673b5e7aac998ffc25b5187090d596787aea70a3d | [
{
"content": "I'm looking into the connection between Alzheimer's disease and Creutzfeldt-Jakob disease. How are these two conditions related?",
"role": "user"
},
{
"content": "They are described as resembling each other, based on similarities found in medical literature co-occurrence.",
"role":... | relation_classification | train | 6a3b05901273ea3b71fd0177a95b1ba9d0c49b0cbbab522d2c9b6fc2522fb4a5 | 1 | 1 | [
"Disease::DOID:10652",
"Disease::DOID:11949"
] | [
"083beaef53820d26316c843b09ac4518a1671de186b6a0f953d3047df81ec063"
] | [
{
"edge_id": "083beaef53820d26316c843b09ac4518a1671de186b6a0f953d3047df81ec063",
"source_id": "Disease::DOID:10652",
"source_name": "Alzheimer's disease",
"relation_id": "Disease-resembles-Disease",
"target_id": "Disease::DOID:11949",
"target_name": "Creutzfeldt-Jakob disease"
}
] | [] | [
"Disease-resembles-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 32} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"MEDLINE cooccurrence"
] | [
"CC BY 3.0",
"CC0 1.0"
] | {"pair_node_ids": ["Disease::DOID:10652", "Disease::DOID:11949"], "structural_split_key": "24f344f960422680ac67a8ff05ecd03203c383e0a0af2a542ae219415b80d95c"} |
ce216d4a00ca5de96437336778813729f80e96244aa3e9c914c38cb3154c4593 | 4fc611a873d4ac19933cef711a9919bbfb99639254f1cb74ca2485f63cbc5907 | [
{
"content": "How is metoprolol connected to hypertension?",
"role": "user"
},
{
"content": "Metoprolol is a disease-modifying treatment for hypertension.",
"role": "assistant"
}
] | relation_classification | train | 5d5179dd2a0158c539d6fb33c2d7502ad99964c7aa1353d612034ce184fc5d80 | 1 | 1 | [
"Compound::DB00264",
"Disease::DOID:10763"
] | [
"8974ab5241f6281b86129ffa4ed1c3960468761195633920c7bb1a9519fab8a5"
] | [
{
"edge_id": "8974ab5241f6281b86129ffa4ed1c3960468761195633920c7bb1a9519fab8a5",
"source_id": "Compound::DB00264",
"source_name": "Metoprolol",
"relation_id": "Compound-treats-Disease",
"target_id": "Disease::DOID:10763",
"target_name": "hypertension"
}
] | [] | [
"Compound-treats-Disease"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"PharmacotherapyDB"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"pair_node_ids": ["Compound::DB00264", "Disease::DOID:10763"], "structural_split_key": "6c4f6964750a1c20f1a55f056f75d3367348254366464ccb400315ccc18709f5"} |
5473f599f78796e50125aaf8cb9546227307a87063e4eeded6fb2edccd62eec9 | 7cea8fcaffc809e29b35c8d47ad8725fe228f1544b78dbcce5a71a9490655fde | [
{
"content": "How are Pazopanib and Cytochrome P450 2C8 Inhibitors connected?",
"role": "user"
},
{
"content": "Pazopanib belongs to the pharmacologic class of Cytochrome P450 2C8 Inhibitors.",
"role": "assistant"
}
] | relation_classification | train | c5dc17921f5342f0f8ad11ba8d8d759ce88ac58f5a315be85159a1174b3ed243 | 1 | 1 | [
"Pharmacologic Class::N0000187062",
"Compound::DB06589"
] | [
"9d23674169f1cb2d80ac608c0c294169d64e465070abdd1dbe716a82c7e44fb8"
] | [
{
"edge_id": "9d23674169f1cb2d80ac608c0c294169d64e465070abdd1dbe716a82c7e44fb8",
"source_id": "Pharmacologic Class::N0000187062",
"source_name": "Cytochrome P450 2C8 Inhibitors",
"relation_id": "Pharmacologic Class-includes-Compound",
"target_id": "Compound::DB06589",
"target_name": "Pazopan... | [] | [
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 20} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"DrugCentral",
"FDA via DrugCentral"
] | [
"CC BY 4.0",
"CC BY-NC 4.0"
] | {"pair_node_ids": ["Compound::DB06589", "Pharmacologic Class::N0000187062"], "structural_split_key": "60e1810f4cb015b1e9fb3be094ceed4fb9541261f7efb98e0204eab3f9b5aaff"} |
daaeef24a2c0dbeb4bd022c84415e2ee6f1ecfd6b761327babe6de385db5e6a5 | b28c64747f776a190fb63470fc96d000ed9339140039eec017c9e33e939228a4 | [
{
"content": "Which anatomical structure is associated with germ cell cancer and expresses the FAM47B gene?",
"role": "user"
},
{
"content": "The testis.",
"role": "assistant"
}
] | multihop_qa | train | f826350e69bae00558329e987657120571b175fd238b62a0e596508aa353a725 | 2 | 2 | [
"Disease::DOID:2994",
"Anatomy::UBERON:0000473",
"Gene::170062"
] | [
"7a811c31b407be66c5baa7121dc3226bba8f7fa7a254fbba0a1dab47f7eabd99",
"72af1b00a10d70a7a2e160e40f0da85f8953d559926d6550f213629ca1ad593c"
] | [
{
"edge_id": "7a811c31b407be66c5baa7121dc3226bba8f7fa7a254fbba0a1dab47f7eabd99",
"source_id": "Disease::DOID:2994",
"source_name": "germ cell cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0000473",
"target_name": "testis"
},
{
"edge_id": "72af1b00... | [
"Anatomy::UBERON:0000473"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 16} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "6365bf544d221eba6cb81cdfcd132e8b3567e82d0d651e1be8a9b93d450b75de"} |
128abc845e114955e8a79913afb341e21c8e7a498672efd62861c639c7318e06 | dffabb302447b694b607385c2ae32b7bc934ae4b075a2a15818a426b2e035428 | [
{
"content": "According to the provided information, what is the anatomical location where thyroid cancer is related to, and which also expresses the IAH1 gene? The facts state that thyroid cancer affects or is related to a specific anatomy, and that same anatomy expresses IAH1.",
"role": "user"
},
{
... | multihop_qa | train | 5859daf8f4adb9a2c776de7c448a9663e8852717ec63ec18c39d10419190c823 | 2 | 2 | [
"Disease::DOID:1781",
"Anatomy::UBERON:0000033",
"Gene::285148"
] | [
"5fad3200f3349706273fddb90fdaa08054acfe1b472b0b79fac113d78e9258b4",
"1296e22edd8bac124cdf2868aad80334e2268e44133b165e9dde1312437eb77a"
] | [
{
"edge_id": "5fad3200f3349706273fddb90fdaa08054acfe1b472b0b79fac113d78e9258b4",
"source_id": "Disease::DOID:1781",
"source_name": "thyroid cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0000033",
"target_name": "head"
},
{
"edge_id": "1296e22edd8b... | [
"Anatomy::UBERON:0000033"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 44} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "a277bdd15d9bb9099d4fbe3dfabe5ac17c557547af0101fb9a73967e54201695"} |
5c21c97714360e54ef7699a5892fdd18617c4baf777a544ab88e521dc91c4dc7 | d8cfe812ef4b2585c455c29cffc6b1c562854178e7e15bbfe08d17210381455f | [
{
"content": "Based on the available biomedical data, which gene links periodontitis to the negative regulation of response to cytokine stimulus? The connection is described as the disease being associated with the gene, and the gene's product participating in the biological process.",
"role": "user"
},
... | multihop_qa | train | b4309793c7e52a85ec1fdb9121fdb25cd8053b1467a41a0a390d56f822997e7f | 2 | 2 | [
"Disease::DOID:824",
"Gene::3557",
"Biological Process::GO:0060761"
] | [
"a8aaebd404477f88a13999af41f3b382a9029cb8a74983188425c04dcfb2ee45",
"cc73000492129b68c2e2b0b7231b86516ec8ca70c0815f8923df0dabd8488d02"
] | [
{
"edge_id": "a8aaebd404477f88a13999af41f3b382a9029cb8a74983188425c04dcfb2ee45",
"source_id": "Disease::DOID:824",
"source_name": "periodontitis",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::3557",
"target_name": "IL1RN"
},
{
"edge_id": "cc73000492129b68c2e2b0b7231b... | [
"Gene::3557"
] | [
"Disease-associates-Gene",
"Gene-participates-Biological Process"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 41} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_gene_biological_process", "structural_split_key": "177f8661b5b39fc67df7656269c67e8cf1410afdcb793cebca720b55df11f5b3"} |
d6d78c2159446c34eba02ce12f9c2d90de07122f2cb39a59bf391ab51729857f | e5e0530bbdd4c0c2f7b06a3c6d30e2a6e3c05f8d48eb7579a896fd02aaaefd4b | [
{
"content": "Can you tell me which part of the body links stomach cancer to the FBN3 gene? I'm looking for the anatomical structure that is affected by stomach cancer and also expresses FBN3.",
"role": "user"
},
{
"content": "The pancreas.",
"role": "assistant"
}
] | multihop_qa | train | 4c976152f88d5bd87cf112599b048f673239d14155a3f9e9c1cb99eb2c5d8af9 | 2 | 2 | [
"Disease::DOID:10534",
"Anatomy::UBERON:0001264",
"Gene::84467"
] | [
"093df18016006fc0f339adcb373c3d391fff415e38ca5f880d4fd64634e01552",
"679d57cdb759e2521cf45ce97be7f695d2925f35aaf7944c479c7f8b7de92154"
] | [
{
"edge_id": "093df18016006fc0f339adcb373c3d391fff415e38ca5f880d4fd64634e01552",
"source_id": "Disease::DOID:10534",
"source_name": "stomach cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001264",
"target_name": "pancreas"
},
{
"edge_id": "679d57c... | [
"Anatomy::UBERON:0001264"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 34} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "6b76ffb4083822100095c1e69b87f7eb503fa5a8c968db44ee690775b580f1b1"} |
965f65b4352d86329e346e683bb46698100fa5bf15d985026dd0377842dfe0c8 | 03ddd882ab2e3c8846fae6b7f89869000aa0f09e5e4373aa9480376c8e9c6f55 | [
{
"content": "Based on the provided evidence, what is the anatomical location that connects bone cancer to the gene NUAK2? The evidence indicates that bone cancer affects or is related to a specific tissue, and that same tissue expresses NUAK2.",
"role": "user"
},
{
"content": "Based on the evidence... | multihop_qa | train | 8b58d29b0b23fbbc2209af7b79c58048a9c59f620964304cef4fd1fc6ad7c6ae | 2 | 2 | [
"Disease::DOID:184",
"Anatomy::UBERON:0002371",
"Gene::81788"
] | [
"8291b627aba71460e9ccb782512816bffb3fd72288d13cf3b5e29361424c04e2",
"1ce56b4b269bf86d045b18bfaa07587ea312ec6aa7a4a0625681f8fd224a1107"
] | [
{
"edge_id": "8291b627aba71460e9ccb782512816bffb3fd72288d13cf3b5e29361424c04e2",
"source_id": "Disease::DOID:184",
"source_name": "bone cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0002371",
"target_name": "bone marrow"
},
{
"edge_id": "1ce56b4b2... | [
"Anatomy::UBERON:0002371"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 53} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "0fdae4c06f84f758537df89c2ebf109a92f0a0a67968ff1d5b67064846113717"} |
6bdeadb46d4c19976459ff214e0db3465429ddae91cef71e8a8c675315102106 | ee5f02ab8b6c41ac493977ae3fecbdf41059c59e67cf2c24463672aca05847b5 | [
{
"content": "Which gene connects acquired immunodeficiency syndrome to the negative regulation of neural precursor cell proliferation, given that the disease is associated with the gene and the gene product participates in that biological process?",
"role": "user"
},
{
"content": "CCR2",
"role"... | multihop_qa | train | 273f6f318c8b0c5a2f259c73dc5383009cebf3e8debf68e5a64e7f66050edd8e | 2 | 2 | [
"Disease::DOID:635",
"Gene::729230",
"Biological Process::GO:2000178"
] | [
"b13ccc7dc93c6b95fb5cab4fd6921aeb4897d13201000d1a2ca3e41cd90f9ee7",
"3b3b3ae4bc6b809ae9f302809d9c2df80db57a8e4350cbac17d2013917ad5122"
] | [
{
"edge_id": "b13ccc7dc93c6b95fb5cab4fd6921aeb4897d13201000d1a2ca3e41cd90f9ee7",
"source_id": "Disease::DOID:635",
"source_name": "acquired immunodeficiency syndrome",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::729230",
"target_name": "CCR2"
},
{
"edge_id": "3b3b3a... | [
"Gene::729230"
] | [
"Disease-associates-Gene",
"Gene-participates-Biological Process"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 34} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "disease_gene_biological_process", "structural_split_key": "d9061d352436ce604581dfe1c719506ff39ebb4bc25c55642cb0a842404f6c2d"} |
e007dccd40b105ef83d57efe7fb5ecf2e3a1518304ba702c30e4357d32b35870 | 40354dd813b03201f2b0cd9fcf7a47c9eebae2d4f77a08303b746b6034fa3801 | [
{
"content": "Which gene is upregulated by Crizotinib and also participates in Heme biosynthesis?",
"role": "user"
},
{
"content": "PPOX",
"role": "assistant"
}
] | multihop_qa | train | cf07495ce08d2abacecfdad23320d79addcd2a13d4967e3099ea894ee7c96a49 | 2 | 2 | [
"Compound::DB08865",
"Gene::5498",
"Pathway::PC7_4443"
] | [
"d3001bbe5d2a12d0401ae1b33781e4651ec11441df3e0198f2cbceb45fb9d272",
"1e8e98003eebbb3b30a2486fb5da0093612c17e816a09ca205eb21fdd60146c0"
] | [
{
"edge_id": "d3001bbe5d2a12d0401ae1b33781e4651ec11441df3e0198f2cbceb45fb9d272",
"source_id": "Compound::DB08865",
"source_name": "Crizotinib",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::5498",
"target_name": "PPOX"
},
{
"edge_id": "1e8e98003eebbb3b30a2486fb5da00... | [
"Gene::5498"
] | [
"Compound-upregulates-Gene",
"Gene-participates-Pathway"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 13} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000",
"Reactome via Pathway Commons"
] | [
"CC BY 4.0",
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "compound_upregulates_gene_pathway", "structural_split_key": "0b7fab734f34d703cf435eec7483105a20a2d8acc9c4d339a8ea84f23b36f74e"} |
8b20b965f86e4a5cbddfe3a7f54e36ef8d4bbb68d0597a7f49c20e7b6f5e5826 | 971e88091dc8ff3223cc7e45d74eb7a427988264ca22abd61e5b25e8de7e235a | [
{
"content": "I'm looking for the anatomical structure that links jejunal cancer to the TRIP11 gene. Specifically, I need to find the anatomy that is affected by jejunal cancer and, at the same time, expresses the TRIP11 gene.",
"role": "user"
},
{
"content": "The anatomical structure is the lymph n... | multihop_qa | train | 073003c9db9c9d0b9347ae587590342c87064759d77589ba2631e3b10f4f4157 | 2 | 2 | [
"Disease::DOID:13499",
"Anatomy::UBERON:0000029",
"Gene::9321"
] | [
"698168593fba9695aab337d10506abdb0fbb6dc91711bc100d8f6bbc6f36528b",
"10c1be21e15b7be75a97b54df7d5959a05e889f5b51662c88d04fb4f978e081e"
] | [
{
"edge_id": "698168593fba9695aab337d10506abdb0fbb6dc91711bc100d8f6bbc6f36528b",
"source_id": "Disease::DOID:13499",
"source_name": "jejunal cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0000029",
"target_name": "lymph node"
},
{
"edge_id": "10c1b... | [
"Anatomy::UBERON:0000029"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 43} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "7cf55da579fe2f351489035728d7fbfc9548c2d798846fbd5a6e2a9590141eb8"} |
944d058a81c9464747233947a2852d815e1bf566e88f21c75d6243aeb2e75ecf | 86b8e959e5ac88dce2bf37f1cda50193fba24e8915881a68466d1186d0d4c7af | [
{
"content": "Which structure connects stomach cancer to TNNT3, given that stomach cancer localizes to it and it expresses TNNT3?",
"role": "user"
},
{
"content": "The lymph node.",
"role": "assistant"
}
] | multihop_qa | train | 3cf788de171d3e7c9d8a136b19e75d908417871c718a3866b997d28029b7089f | 2 | 2 | [
"Disease::DOID:10534",
"Anatomy::UBERON:0000029",
"Gene::7140"
] | [
"ed10759c4f46117b27dbf5ee091705855d026b6215e8ad9ec257b83fde738504",
"f85f643962106281aa45fae24bc4196cdf1743a0798d7547f3a1e6ac9fe69a51"
] | [
{
"edge_id": "ed10759c4f46117b27dbf5ee091705855d026b6215e8ad9ec257b83fde738504",
"source_id": "Disease::DOID:10534",
"source_name": "stomach cancer",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0000029",
"target_name": "lymph node"
},
{
"edge_id": "f85f6... | [
"Anatomy::UBERON:0000029"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 21} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "f1d2d6862ed591bafa0a2de044ed7eba99794e9cdb24f92305ba3c0795e53fba"} |
3ce698b1a06c56053de91bc0a8991c2101f1caa8ae4568ee11524d997699964f | 31a75ca282c2444dd917162ecb88d4263061633afbcc6521258fa419c0c2dfdd | [
{
"content": "I'm researching the biological link between malignant mesothelioma and the gene SCGB1D2. Specifically, I'm looking for the anatomical site where the disease is known to occur that also expresses this gene. Do you have that information?",
"role": "user"
},
{
"content": "The anatomical s... | multihop_qa | train | 2b7926ba1d04c9c0d91e0d1db413b741afe792e73cd4a75669cda032cb2dfa8d | 2 | 2 | [
"Disease::DOID:1790",
"Anatomy::UBERON:0002450",
"Gene::10647"
] | [
"d225785d0d2b51033400934e6a4eb7bcd9e4d7a918ee6cdd792d79dd4a8aedc6",
"8d219a33b614d9d86e5fba9bd8ab6fba50b4ad4bb5ad6da0f437b9103b04ee22"
] | [
{
"edge_id": "d225785d0d2b51033400934e6a4eb7bcd9e4d7a918ee6cdd792d79dd4a8aedc6",
"source_id": "Disease::DOID:1790",
"source_name": "malignant mesothelioma",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0002450",
"target_name": "decidua"
},
{
"edge_id": "8... | [
"Anatomy::UBERON:0002450"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 50} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "62102abdae57c833789442fa9505ecb4cc3e4d41f9aa81b8a6ee81ffea975024"} |
5182446200c0866f1541a943dc8b4f0ae33bf7e9116fc42569acbb40ef71c79b | 8643cdec6039983096ba73d13bf860bdf3ab0ec454f8de0d824ad453e9151847 | [
{
"content": "I'm trying to understand the biological link between panic disorder and the gene ETV6. What anatomical structure serves as the connection, where panic disorder localizes and that same structure expresses this gene?",
"role": "user"
},
{
"content": "The brain.",
"role": "assistant"
... | multihop_qa | train | 016414cf0c43bc374819d16a47d7900b30f00fea415db8618a89721ea759c8fe | 2 | 2 | [
"Disease::DOID:594",
"Anatomy::UBERON:0000955",
"Gene::2120"
] | [
"3c39433c225b0a1f0f1f381216dc891062429b8c340b2a0ee04053c4e6c658b2",
"b3752c5d1fcd3d38e80395e819db6a4f2b3f0a9d4db35b96e0ae909e8369ec50"
] | [
{
"edge_id": "3c39433c225b0a1f0f1f381216dc891062429b8c340b2a0ee04053c4e6c658b2",
"source_id": "Disease::DOID:594",
"source_name": "panic disorder",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0000955",
"target_name": "brain"
},
{
"edge_id": "b3752c5d1fcd... | [
"Anatomy::UBERON:0000955"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 34} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "8d3781279c55738aa5fa0dad1fc01a05b31a592e64a313dba47ee4656d7f62fc"} |
3f76af9533a2ab38ed6404be31202574e2bd5abd73a435b50088845e13de6a68 | 420ccbed73e7300511783c35c0510528f8f89b66bed516c5e35742e968cd0b30 | [
{
"content": "What anatomical structure is linked to both Barrett's esophagus and the BRD2 gene? I know that Barrett's esophagus affects smooth muscle tissue, and that tissue expresses the BRD2 gene.",
"role": "user"
},
{
"content": "Smooth muscle tissue.",
"role": "assistant"
}
] | multihop_qa | train | ae63c3604baf77d261342a6012f0cd62f2d4e72bd2f317ed4f80081693e11356 | 2 | 2 | [
"Disease::DOID:9206",
"Anatomy::UBERON:0001135",
"Gene::6046"
] | [
"ee4b772c7db84ff2afc9b9d91ab3cb0c445f80506da79ccdefcc6a546a28f242",
"9a02a620be80ac6a1a1bff5069c505f1cbff81784a718d3c963bc0a33ab9aa23"
] | [
{
"edge_id": "ee4b772c7db84ff2afc9b9d91ab3cb0c445f80506da79ccdefcc6a546a28f242",
"source_id": "Disease::DOID:9206",
"source_name": "Barrett's esophagus",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001135",
"target_name": "smooth muscle tissue"
},
{
"ed... | [
"Anatomy::UBERON:0001135"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 32} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "fbf89764b85767c92659be5a695bcd061db2af9601b1c1ef1198dc11b8fb40ff"} |
f877ab2d73d30dd8cdb91debca19707595e96bdd0e9c6da280a1f159b3fbea98 | 8b006c7dadec48497e9ac96e51898885dacf61506633734922ceb8ed12b7e366 | [
{
"content": "What anatomical structure links hypertension to the DCDC2 gene, given that the disease affects the structure and the gene is expressed within it?",
"role": "user"
},
{
"content": "The central nervous system.",
"role": "assistant"
}
] | multihop_qa | train | b13e20a60a50c320f169fb3e909c45d93de03dc139736c886e9a291337023549 | 2 | 2 | [
"Disease::DOID:10763",
"Anatomy::UBERON:0001017",
"Gene::51473"
] | [
"15a9e10f5e2761ec789560b10712b3102dcf6ffb97c024fe1762c0d147e35f19",
"3132e060c3240ccc493a577731e8266ce0e7e2a32c20d809399a8c17ed6bd1f8"
] | [
{
"edge_id": "15a9e10f5e2761ec789560b10712b3102dcf6ffb97c024fe1762c0d147e35f19",
"source_id": "Disease::DOID:10763",
"source_name": "hypertension",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001017",
"target_name": "central nervous system"
},
{
"edge_i... | [
"Anatomy::UBERON:0001017"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 27} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "33faab207edbe5413df0246af8c5ed2cb0afc4e6918827917a6bb88f0861473b"} |
c634be98687683e6500cf1ca08665b5ebf092801b96e8425c2e4a3a5c15ed2a7 | cc9a7539e3eaf99b4c352c99b8856e2c16b4726c04d38d29ae132cb0425c0f5b | [
{
"content": "I'm researching the connection between intracranial aneurysm and the TMEM167B gene. Can you tell me which specific anatomical structure is involved in both conditions—where the disease localizes and which tissue expresses that gene?",
"role": "user"
},
{
"content": "The brain is the an... | multihop_qa | train | 37dd2e295c319c3b1b11381d5ed5a2b1642cc058d07fb5306c9651f70625c4f3 | 2 | 2 | [
"Disease::DOID:10941",
"Anatomy::UBERON:0000955",
"Gene::56900"
] | [
"262c24cdf1da86af4a5bfe06b703a6e376c9af0867f83594840fca143741d357",
"d6c0d861c021f5f222bb3d29977c4a568da399b04513c104aeeff8b9cadc7826"
] | [
{
"edge_id": "262c24cdf1da86af4a5bfe06b703a6e376c9af0867f83594840fca143741d357",
"source_id": "Disease::DOID:10941",
"source_name": "intracranial aneurysm",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0000955",
"target_name": "brain"
},
{
"edge_id": "d6c... | [
"Anatomy::UBERON:0000955"
] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 61} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_anatomy_expressed_gene", "structural_split_key": "4deb7c5c0bddf1f68014a33d33228a0ab0f5b790e54f88a753a16e4c3d4aea9e"} |
c90b541ef35b06822d5f6a8d10c96cdc0c99fe3e6752d9deb5c5f2a2b0d12d53 | fb4bf35dcd683224b53d7002feb6d54d377339d3dfc03a7e0af2e723b1953340 | [
{
"content": "Which gene is upregulated by Homoharringtonine and participates in the Hypothetical Network for Drug Addiction?",
"role": "user"
},
{
"content": "TERF2IP",
"role": "assistant"
}
] | multihop_qa | train | 773d849926b4c882918658718b04e63d4d0938f639e48431e5c0c054cf9438c6 | 2 | 2 | [
"Compound::DB04865",
"Gene::54386",
"Pathway::WP666_r68893"
] | [
"fd626e8f7b1ce02e1c3d81d945770b7874070c187e118e72ca2ae33d478dd61c",
"0920695814027ddc1ef2f6d931fc8d8e09c3c8a42bb42b1b2344fc6dfcd6ab0e"
] | [
{
"edge_id": "fd626e8f7b1ce02e1c3d81d945770b7874070c187e118e72ca2ae33d478dd61c",
"source_id": "Compound::DB04865",
"source_name": "Homoharringtonine",
"relation_id": "Compound-upregulates-Gene",
"target_id": "Gene::54386",
"target_name": "TERF2IP"
},
{
"edge_id": "0920695814027ddc1ef... | [
"Gene::54386"
] | [
"Compound-upregulates-Gene",
"Gene-participates-Pathway"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 16} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"DrugBank",
"Entrez Gene",
"LINCS L1000",
"WikiPathways"
] | [
"CC BY 3.0",
"CC BY-NC 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "compound_upregulates_gene_pathway", "structural_split_key": "992a3ac57175c20ea3cd8bb1e0a5e2224d073526b6cf15e62f2a59da3c53533b"} |
035323d77cc6a40d0218cd89d7445de12a0a3022b6e00c990c2877333799ce5d | 2961953e570b5a8d5cadc672ae768739dd12f50982540cecbb6114cb1a15b1ee | [
{
"content": "What protein product links the drug Tocainide to IgA glomerulonephritis, given that Tocainide binds this protein and the disease is associated with it?\n\nEvidence:\n- Tocainide binds the protein product of ALB.\n- IgA glomerulonephritis is associated with ALB.",
"role": "user"
},
{
"c... | multihop_qa | train | 0d1d2fb114a9554200c771f45344e45bbecc16fc981a2cdb527f2cdb68a6ca49 | 2 | 2 | [
"Compound::DB01056",
"Gene::213",
"Disease::DOID:2986"
] | [
"e12f6c2f36a8fefa2d6e654ddc566d86170c92ef910f53e00b3042d1476e5f88",
"c0f651d876db5b0947233614339e40bb6f3e2a6bc6158e9a8ae9dee51e902ea4"
] | [
{
"edge_id": "e12f6c2f36a8fefa2d6e654ddc566d86170c92ef910f53e00b3042d1476e5f88",
"source_id": "Compound::DB01056",
"source_name": "Tocainide",
"relation_id": "Compound-binds-Gene",
"target_id": "Gene::213",
"target_name": "ALB"
},
{
"edge_id": "c0f651d876db5b0947233614339e40bb6f3e2a6... | [
"Gene::213"
] | [
"Compound-binds-Gene",
"Disease-associates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 40} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"DrugBank",
"Entrez Gene",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC BY-NC 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": true, "metapath": "compound_binds_gene_associated_disease", "structural_split_key": "8fcac7e479166c6529affb704b69b2f9f220235cf432ab109fbf281da26a8a19"} |
e780ddb1743362c598a1de164aa14986339d3e82fe9f7b9f0db48c378f5aa77b | 36b00d75580007508e8a2f4607d45ac8d9e451d9823e38001ec3fc00fb4fe7f4 | [
{
"content": "I'm looking for a gene that links sarcoma to the positive regulation of proteasomal protein catabolic process. Can you identify it?",
"role": "user"
},
{
"content": "The gene that connects sarcoma to the positive regulation of proteasomal protein catabolic process is MDM2.",
"role"... | multihop_qa | train | 1e733807ac16b30477b3743750bd3c5120795437ec74afb498d301ce8fa19a8f | 2 | 2 | [
"Disease::DOID:1115",
"Gene::4193",
"Biological Process::GO:1901800"
] | [
"4afe42cf73ce7ff4963a9a896fcc6aa2af7a981772ee38ab114ffd11bfb04c8c",
"81cdf17c03af4ff34719fc3380243d99dddd39eb303713239ea21df86639add3"
] | [
{
"edge_id": "4afe42cf73ce7ff4963a9a896fcc6aa2af7a981772ee38ab114ffd11bfb04c8c",
"source_id": "Disease::DOID:1115",
"source_name": "sarcoma",
"relation_id": "Disease-associates-Gene",
"target_id": "Gene::4193",
"target_name": "MDM2"
},
{
"edge_id": "81cdf17c03af4ff34719fc3380243d99dd... | [
"Gene::4193"
] | [
"Disease-associates-Gene",
"Gene-participates-Biological Process"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 37} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go",
"UNSPECIFIED"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"answer_mode": "bridge", "context_grounded": false, "metapath": "disease_gene_biological_process", "structural_split_key": "13da8dd7e157cafe4e81f6dff9fb0ac2b131b7952da3edadc04e989b84e55c4b"} |
f40769460e41c84552ee679fe8a623e618187cb9fae4259cea5bd05715c4f384 | b5a6f7d5705afe230af2ddc35a07a871d73f1d8ffb3b570f9f5bcd37e53bc1c9 | [
{
"content": "Here are some facts I've collected:\n- UQCR10 participates in oxidoreductase activity, acting on diphenols and related substances as donors\n- CYP1A1 participates in oxidoreductase activity, acting on diphenols and related substances as donors\n- UQCRQ participates in oxidoreductase activity, acti... | graph_to_text | train | b6c368e84af84f4c11983101ffaa8eee576faa713e63fd6202632a2b47aac6ef | 7 | 1 | [
"Gene::29796",
"Molecular Function::GO:0016679",
"Gene::1543",
"Gene::27089",
"Gene::7388",
"Gene::7384",
"Gene::10975",
"Gene::7386"
] | [
"8cfa008fae4763469f03037f46f6e12c3d941851759bb7c7943ce667de778b09",
"31fcc184b0ea19268c385fb0a4c89f80e5151b2221c70317ee267c49955d31ca",
"06d5fde63342ccf76abd5b78b7ee7be366a184bf2c14dab1de7631efb4df8fc5",
"933fa9101fce8577488bcbaa24235c3c7e7fe2f37aeb624841ed9624d60baaa8",
"cd07e9ffaf7f04ef44caecf828508ffaf86... | [
{
"edge_id": "8cfa008fae4763469f03037f46f6e12c3d941851759bb7c7943ce667de778b09",
"source_id": "Gene::29796",
"source_name": "UQCR10",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0016679",
"target_name": "oxidoreductase activity, acting on diphe... | [] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 131} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"structural_split_key": "3aaadcc0863aa871bbbc2ee17d11ad1286782cc1e1019fe15aefef6c0f183230"} |
3ef4e881154618c49b82bd406024cdb26a6a4088d72d44a38485470f1042eb1a | a616cc0931bb6c8a852da6293608f0e2b38d5542fb612537ef8b3b5564731f52 | [
{
"content": "Here are some facts about Penicillin V:\n- It can cause tongue discolouration.\n- It chemically resembles Mezlocillin.\n- Exposure to it downregulates the MTERF3 gene.\n- It can cause urticaria.\n- Exposure to it downregulates the RRP1B gene.\n- It is included in the pharmacologic class of Penicil... | graph_to_text | train | 86f55516e6d9b87a5941416ac1a1ecd6d30fa4c48811d213d76967d9bcc34440 | 7 | 1 | [
"Compound::DB00417",
"Side Effect::C0151596",
"Compound::DB00948",
"Gene::51001",
"Side Effect::C0042109",
"Gene::23076",
"Pharmacologic Class::N0000011281",
"Compound::DB00739"
] | [
"059fb410f610127698c47bb55f1917a1b18424dde3649936126c350345c064d0",
"18a0fe198154d8db19766daea77d5449ecedec3ff03ebf8ca0d0e41b9e6bd396",
"aa95f394e4b68a683a39e8e8eecccd507389245058b32af70a73f4d05b613b06",
"f76c3c2fb3f618c84519ae04272e643d8924ba4f449b3e6e3a2df65052d0b161",
"2965d13fd0fe7a002dedf7171281a974682... | [
{
"edge_id": "059fb410f610127698c47bb55f1917a1b18424dde3649936126c350345c064d0",
"source_id": "Compound::DB00417",
"source_name": "Penicillin V",
"relation_id": "Compound-causes-Side Effect",
"target_id": "Side Effect::C0151596",
"target_name": "Tongue discolouration"
},
{
"edge_id":... | [] | [
"Compound-causes-Side Effect",
"Compound-resembles-Compound",
"Compound-downregulates-Gene",
"Pharmacologic Class-includes-Compound"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 100} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Dice similarity of ECFPs",
"DrugBank",
"DrugCentral",
"Entrez Gene",
"FDA via DrugCentral",
"LINCS L1000",
"SIDER 4.1",
"UMLS via SIDER 4.1"
] | [
"CC BY 4.0",
"CC BY-NC 4.0",
"CC BY-NC-SA 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"structural_split_key": "951946b415dfa7430f9f944a85597f64538c1b1f1706b3276ee8ed438a5beb9f"} |
2366b5da1f2e973984c50686be6d96f71753ee56eee3ebaf857580e36a158476 | 805e1c0e7b89cde91f670422f0469c006d67bcf2e8075b8464da7da99e708f31 | [
{
"content": "Can you summarize these facts for me?\n- Otosclerosis is related to the semicircular canal.\n- The semicircular canal expresses the BMP4, OTOP1, HMX3, UBIAD1, and CHD7 genes.\n- Head and neck cancer is also related to the semicircular canal.",
"role": "user"
},
{
"content": "Otoscleros... | graph_to_text | train | 1ddc98f467a3efd2293048c2e3d466e6739c45d104ceff1d229c8072b17a2d1d | 7 | 1 | [
"Disease::DOID:12185",
"Anatomy::UBERON:0001840",
"Gene::652",
"Gene::133060",
"Gene::340784",
"Gene::29914",
"Gene::55636",
"Disease::DOID:11934"
] | [
"95a2ae72b1ff01cab1c2721e54f4fd18a3d25eb5b986d65d27ce73ea20a4dd12",
"36deaad96a05414bde7b44eab8521cacfe1444cb3d5297b45bb4ece62338ac47",
"4e495842ab194bef8ce53861c14b249862a71413ba448f5787ffec2c23a558a0",
"87009e05a21a1b73d23fb228c2953b402c6f4a8b1627b1ccdc47507de3fa1699",
"b67286d52e22fe4070e1f61a110cc1a2315... | [
{
"edge_id": "95a2ae72b1ff01cab1c2721e54f4fd18a3d25eb5b986d65d27ce73ea20a4dd12",
"source_id": "Disease::DOID:12185",
"source_name": "otosclerosis",
"relation_id": "Disease-localizes-Anatomy",
"target_id": "Anatomy::UBERON:0001840",
"target_name": "semicircular canal"
},
{
"edge_id": ... | [] | [
"Disease-localizes-Anatomy",
"Anatomy-expresses-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 66} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Disease Ontology",
"Entrez Gene",
"MEDLINE cooccurrence",
"UNSPECIFIED",
"Uberon"
] | [
"CC BY 3.0",
"CC BY 4.0",
"CC0 1.0"
] | {"structural_split_key": "f4aa1a4e7a0d1b4ba01f30978c7269653430806c8796c35e2ce01bbdc6695397"} |
1b1a4fac773f56961e517c3e442e0906aeb93ed83c73a3f09cd8b34de56ead3a | 1a2621a11aed9e441e23a0861390c4dc92d6575efe1a9dd448dfc7bba0d606fa | [
{
"content": "I have a few notes from a biomedical database:\n\n- FADS2 is linked to acyl-CoA desaturase activity.\n- SCD5 is linked to acyl-CoA desaturase activity.\n- SCD is linked to acyl-CoA desaturase activity.\n\nCan you summarize these facts concisely without adding any external information?",
"role"... | graph_to_text | train | fc8382d8eaa4d0ce09fa0d9fec5714ca8706c792f13a223cc1c449c5997efffb | 3 | 1 | [
"Gene::9415",
"Molecular Function::GO:0016215",
"Gene::79966",
"Gene::6319"
] | [
"14aa42655b81f18297f7e2137e9a891263f3eac221bfc3688e80d6e2697ea589",
"634502fd0203b41afdeaf0c9d89c9a6e72d44b5c243cb7e2824772a88f78bbc6",
"589ae2bc2f6c427f3716d5db86e164fe71baebe2000abfbca6825045ec8006fe"
] | [
{
"edge_id": "14aa42655b81f18297f7e2137e9a891263f3eac221bfc3688e80d6e2697ea589",
"source_id": "Gene::9415",
"source_name": "FADS2",
"relation_id": "Gene-participates-Molecular Function",
"target_id": "Molecular Function::GO:0016215",
"target_name": "acyl-CoA desaturase activity"
},
{
... | [] | [
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 80} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"structural_split_key": "cae604db0a478620d5ef89fe2d4d2a020bfead577b8d76e1ded8e52c071748fe"} |
bc5bf3a4075ff2ba362b4d39f37786b434e4f892d0745b5d204ba9ed2852dcaa | 98e15a8586475461b055a9a62edd675e6db8b1536e6013647463e4d8faf7cb1f | [
{
"content": "Here are some notes on the NYX gene:\n- It is involved in the cellular response to cytokine stimulus.\n- It plays a role in sensory perception.\n- It evolutionarily covaries with SYNDIG1L.\n- It has the molecular function of enzyme regulator activity.\n- It is involved in the regulation of protein... | graph_to_text | train | aa396af25c4f0dd5819bf6e35e1352a299cd1b4e56f5526979cc2539d2ac80c8 | 7 | 1 | [
"Gene::60506",
"Biological Process::GO:0071345",
"Biological Process::GO:0007600",
"Gene::646658",
"Molecular Function::GO:0030234",
"Biological Process::GO:0045859",
"Molecular Function::GO:0019207",
"Molecular Function::GO:0019210"
] | [
"16c6dd46e29025758b383e1909dd4f8bb1c6da2c1c661889afd4bdedbf8b596f",
"fdd92af302caf1db84d060a32cbd7180c616cb211178cccbe6be843bd82e8fc0",
"460da531145d122850e5b2384ef43595f43764a330422769477ed512a7a0fb0a",
"8f4eb2724e60720d97e3d88ea3f5a085f03c69bcbc57d5d7c738df846f658dab",
"305e0e8300849759a2e499be39d7a18b63e... | [
{
"edge_id": "16c6dd46e29025758b383e1909dd4f8bb1c6da2c1c661889afd4bdedbf8b596f",
"source_id": "Gene::60506",
"source_name": "NYX",
"relation_id": "Gene-participates-Biological Process",
"target_id": "Biological Process::GO:0071345",
"target_name": "cellular response to cytokine stimulus"
}... | [] | [
"Gene-participates-Biological Process",
"Gene-covaries-Gene",
"Gene-participates-Molecular Function"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 135} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"ERC",
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0",
"UNSPECIFIED"
] | {"structural_split_key": "053521f4f37b53e4556c2f6a594dfad527d81713132353bbe97c36b4f19a60ba"} |
8f01db31dc9677303449141865b0a66765b04585a0b550ca80cb7d8484b9302f | 9514278607635f8ae3d6cb8f40571089efb4ec25a77be38bb34ce2f2207db595 | [
{
"content": "Based on the text provided, can you list the genes and their involvement in the positive regulation of inflammatory response to antigenic stimulus?\n\nText:\nThe product of TNF participates in positive regulation of inflammatory response to antigenic stimulus. The product of CNR1 participates in p... | text_to_graph | train | c26213dc8a3bd734d3d572b6eeb5fb609a8183a052b7a21de459bc76e92db8c4 | 7 | 1 | [
"Gene::7124",
"Biological Process::GO:0002863",
"Gene::1268",
"Gene::4049",
"Gene::1236",
"Gene::2205",
"Gene::2207",
"Gene::7784"
] | [
"f63a74b419c1b0d92392e6deae225058bd0040e402633b04186332e25d370588",
"dbbe23f9f728f109e84e9fdd6bacad6364014c73f43d6d63b018c2322fcb9bca",
"80edc3d6ccd38769c0e053bed68bb51e80b6d718b98876f5fb5df76c6509be70",
"5bf885afc2d1eab478e02d86d9353d462092e2c99635a464e9d29bb080ea256d",
"3f44493bad91e50d384793ecb590ba94bf0... | [
{
"edge_id": "f63a74b419c1b0d92392e6deae225058bd0040e402633b04186332e25d370588",
"source_id": "Gene::7124",
"source_name": "TNF",
"relation_id": "Gene-participates-Biological Process",
"target_id": "Biological Process::GO:0002863",
"target_name": "positive regulation of inflammatory response... | [] | [
"Gene-participates-Biological Process"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 154} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"structural_split_key": "da8683c93ee9cb4d29310505cbe25b787446d6d3da1f69c33e15d7d53d634039"} |
f4f868c3de8b2775290b553b9c97b02048a4723e31f6d40e36c2c1f135f6c14a | 044a80dd60d9ac4d3ee81ec4d0b9f13408dfab9d47596e494e0e20eba5afc5ec | [
{
"content": "Based on the text below, please list the connections between genes and biological processes. For each connection, state the gene and the process it is involved in.\n\nThe product of EFNA5 participates in regulation of cell morphogenesis involved in differentiation. The product of RAC1 participates... | text_to_graph | train | cc5cb70e202e88a8eedc493099dfafcca6b87683d5465845e720509bb751fdb4 | 7 | 1 | [
"Gene::1946",
"Biological Process::GO:0010769",
"Gene::5879",
"Gene::6498",
"Gene::348262",
"Gene::11178",
"Gene::55604",
"Gene::6049"
] | [
"fc73cfb46ed2e7d3076add4ae75de27e1b5369038b137a8417b60629995f9f08",
"8e2720b8a70eb825b10df448e4395ebf5f599c4152386308dc7a52c72e97085a",
"e04c0e6c1abe056f0045f77b46be9073e8110449bb7f056c7d872b9ddcef2be8",
"934ec4525fe7fcc95e5e26d55edbd3896a90adfab0f0fea7d6f380f73124d7cb",
"36a7f2de89b5f9e1cc55c7ec6da9dc0717e... | [
{
"edge_id": "fc73cfb46ed2e7d3076add4ae75de27e1b5369038b137a8417b60629995f9f08",
"source_id": "Gene::1946",
"source_name": "EFNA5",
"relation_id": "Gene-participates-Biological Process",
"target_id": "Biological Process::GO:0010769",
"target_name": "regulation of cell morphogenesis involved ... | [] | [
"Gene-participates-Biological Process"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 203} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"Gene Ontology",
"NCBI gene2go"
] | [
"CC BY 4.0",
"CC0 1.0"
] | {"structural_split_key": "0912a94b7be8e451fc684e82ac889cb2f5319e4cd7bfeee6b2806c8f6070535e"} |
c483a26c4ea1ae10ead0d91300931fdbd1a19976a96512b21fb055338a403d22 | a7240cfb6cf76166747a0bf33c4d4c2575f2d3e5a1beadf18e54a0009a8df506 | [
{
"content": "Based on the text provided, what are the specific gene regulation relationships mentioned? Please list each one clearly.\n\nAQP12A regulates SAR1B. AQP12A regulates BABAM1. AQP12A regulates CDKN1A. AQP12A regulates RND3. AQP12A regulates MED24. AQP12A regulates XPNPEP1. AQP12A regulates TIMELESS."... | text_to_graph | train | b2f817bea64377db00b19eb97d1edc1c4bf2c4b9fa38d060fc6ea1ef9f507013 | 7 | 1 | [
"Gene::375318",
"Gene::51128",
"Gene::29086",
"Gene::1026",
"Gene::390",
"Gene::9862",
"Gene::7511",
"Gene::8914"
] | [
"4494b13cdd297f880febcb392c544301ab65a2026bcee21bedcb7fa149c6adb4",
"e258dc137ec4a90bc57a8399121b9972000e0856a4b7f3528d39c9594c21a2a3",
"d02716cb9a4363db8694473b656950ed1347634b1f58f1129fbd4f06ad24a5e2",
"70457a8d1f998c403f8b41430ab1b9b1983b411ee8ce76197d56f4e2b25a0824",
"da226a758649f9b209962204199611bc34b... | [
{
"edge_id": "4494b13cdd297f880febcb392c544301ab65a2026bcee21bedcb7fa149c6adb4",
"source_id": "Gene::375318",
"source_name": "AQP12A",
"relation_id": "Gene-regulates-Gene",
"target_id": "Gene::51128",
"target_name": "SAR1B"
},
{
"edge_id": "e258dc137ec4a90bc57a8399121b9972000e0856a4b... | [] | [
"Gene-regulates-Gene"
] | none | llm | fixed-v3+natural-conversation-v2 | Qwen/Qwen3.6-35B-A3B | {"deterministic": true, "message_tokens": 62} | hetionet | v1.0 | a342ab57e9073e6c02bb5e109d1f16917e6f933be4e5c77ebbaebfa26b984c19 | [
"Entrez Gene",
"LINCS L1000"
] | [
"CC0 1.0",
"UNSPECIFIED"
] | {"structural_split_key": "85477bdd64e4de6c9892b0ee3bd173f5e3cd4cb5e7c01f5bc4a74c8ae88e8281"} |
synth-kg-text: hetionet v1.0
This repository contains validated chat-style supervised fine-tuning data generated by synth-kg-text.
- Source run: sglang-smoke-2
- Knowledge graph: hetionet v1.0
- Generator model: Qwen/Qwen3.6-35B-A3B
- Configuration hash: b6c36da6ccc0bae1b024c308a07d25f2e53f38252fd3d954c57ed68baaa7189e
Splits
| Split | Rows |
|---|---|
| train | 75 |
| validation | 5 |
| test | 3 |
| seen_fact_unseen_phrasing | derived evaluation subset |
| compositional | derived evaluation subset |
The metadata directory contains the resolved configuration, prompt snapshots, build manifest, and generation report needed to audit the run. Individual records retain graph provenance, licenses, grounding identifiers, and validation results.
Load
from datasets import load_dataset
dataset = load_dataset("giannor/test2")
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