output stringlengths 15 2.78k ⌀ | instruction stringlengths 12 86 | input stringclasses 1
value |
|---|---|---|
Patients who appear mildly intoxicated may be simply managed with supportive care only. An ethanol concentration is generally not needed for management. Patients can be discharged when they are not clinically intoxicated (no ataxia, nystagmus, or slurred speech). Significant CNS depression indicates a more severe poiso... | MILD TO MODERATE Ethanol TOXICITY | |
Measure a serum ethanol level if ethanol is believed to be the cause of altered mental status, and consider and rule out other reversible causes of altered mental status, such as hypoglycemia, hypoxia, and opiate intoxication. Patients who are comatose may require airway protection. Other causes of altered mental statu... | SEVERE Ethanol TOXICITY | |
Mild to Moderate AWS:
Benzodiazepines are central to treatment, administered either orally or intravenously.
Aim to control withdrawal symptoms and prevent seizures.
For mild AWS, a long-acting benzodiazepine like clorazepate may be used, starting with 30 mg and then 15 mg 2 to 4 times daily, tapering Over 4-5 days.
Mo... | Sudden cessation of chronic ethanol | |
Fluid resuscitation should be initiated immediately, but care must be taken to recognize pulmonary and cerebral edema when present. When a significant acute ingestion is confirmed, chelation therapy should be initiated immediately prior to laboratory confirmation. This will minimize time delay to treatment associated w... | MILD TO MODERATE Arsenic TOXICITY | |
Aggressive life support measures should be instituted immediately. Anti-arrhythmic medications that prolong the QTc should be avoided. In severely ill patients, combined therapy with both BAL and an oral agent should be considered. If renal failure exists, the dose of BAL should be decreased after the loading dose. | SEVERE acute Arsenic TOXICITY | |
Activated charcoal may be given if patients present shortly after ingestion, and are awake and alertwith a protected airway | MILD TO MODERATE Phenobarbital TOXICITY | |
Orotracheal intubation for airway protection should be performed if patient is increasingly drowsy or comatose. Administer activated charcoal (GI decontamination should be performed only in patients who can protect their airway or who are intubated). Severe hypotension and hypothermia may develop; aggressive supportive... | SEVERE Phenobarbital TOXICITY | |
Symptomatic and supportive care in all patients. Monitor for progression of sedation. Repeat valproic acid levels every 4 to 6 hours and consider multidose activated charcoal if the level is continuously rising. | MILD TO MODERATE Valproic acid TOXICITY | |
Resuscitation, symptomatic and supportive care in all patients. Early intubation in patient with declining level of consciousness. Hypotension: Treat with IV fluids, if no response start vasopressors. Consider hemodialysis in patients with severe toxicity who are not responding to supportive care. Consider carnitine in... | SEVERE Valproic acid TOXICITY | |
Treatment of mild to moderate toxicity is largely supportive. Sinus tachycardia should be treated with fluid resuscitation and benzodiazepines for anticholinergic symptoms. Dystonic reactions can be treated with anticholinergic medications, such as diphenhydramine 25 mg, or benzodiazepines if the patient is also exhibi... | MILD TO MODERATE Carbamazepine TOXICITY | |
Supportive care is the mainstay of treatment. Specific interventions based on the system of toxicity are as follows:
a) CNS: Mental status depression may require airway protection. Coma should be treated with airway management and supportive care. Seizures should be treated with benzodiazepines as first-line therapy f... | Severe Carbamazepine TOXICITY | |
Establish IV access and place the patient on a cardiac monitor. Treat nausea with an antiemetic and administer IV fluids. Monitor electrolytes | MILD TO MODERATE Theophylline TOXICITY | |
The primary effect of theophylline is increased sympathomimetic effects. The primary treatment is sedation with benzodiazepines (such as lorazepam 1 to 2 mg IV every 5 min titrated to effect); high doses may be required. Hemodynamically significant tachycardia should be treated with esmolol, which can paradoxically imp... | SEVERE Theophylline TOXICITY | |
The primary effect of theophylline is increased sympathomimetic effects. The primary treatment is sedation with benzodiazepines (such as lorazepam 1 to 2 mg IV every 5 min titrated to effect); high doses may be required. Hemodynamically significant tachycardia should be treated with esmolol, which can paradoxically imp... | CHRONIC Theophylline TOXICITY | |
Most acute lithium Overdoses may be safely managed with supportive care that includes: antiemetics for nausea and vomiting, intravenous normal saline hydration to enhance renal lithium elimination, and correction of any electrolyte abnormalities | MILD TO MODERATE acute Lithium TOXICITY | |
For chronic toxicity, address underlying causes of decreased renal clearance, including intravenous fluids for dehydration or discontinuing medications that impair renal function. | MILD TO MODERATE chronic Lithium TOXICITY | |
Orotracheal intubation for airway protection should be performed if recurrent seizures, increasing somnolence or coma develop. Administer intravenous normal saline to enhance renal elimination of lithium (Goal: urine output of 2 to 3 mL/kg/hr). Intravenous fluids and vasopressors (dopamine, norepinephrine) may be neede... | SEVERE chronic Lithium TOXICITY | |
The primary concerns of mild to moderate toxicity from lead exposure in young children are neurodevelopmental, specifically lower intelligence quotient scores and behavioral problems. Population studies suggest that mild cognitive impairment develops at low levels of lead exposure (blood lead concentrations of 10 mcg/d... | Mild to Moderate Lead Toxicity | |
Acute ingestions of very large amounts of lead are rare, but may cause abdominal pain, nausea, vomiting, anemia (usually hemolytic), toxic hepatitis, and encephalopathy. In children, severe toxicity manifests as encephalopathy (ie, coma, seizures, ataxia, incoordination, cranial nerve palsies, increased intracranial pr... | Severe Lead Toxicity | |
Patients who do not develop significant cardiac toxicity require only supportive care and monitoring. Patients with mild bradycardia and nonspecific symptoms from chronic poisoning should be monitored and rehydrated, but do not require specific therapy. | Mild to Moderate Acute Digoxin Toxicity | |
Patients who do not develop significant cardiac toxicity require only supportive care and monitoring. Patients with mild bradycardia and nonspecific symptoms from chronic poisoning should be monitored and rehydrated, but do not require specific therapy. | Mild to Moderate Chronic Digoxin Toxicity | |
Following acute ingestion, patients with hyperkalemia (greater than 5 mEq/L), symptomatic bradycardia, ventricular ectopy, or dysrhythmias should be treated with digoxin immune Fab. Digoxin immune Fab is also indicated for patients with chronic toxicity with ventricular ectopy or symptomatic bradycardia. If digoxin imm... | Severe Acute Digoxin Toxicity | |
Following acute ingestion, patients with hyperkalemia (greater than 5 mEq/L), symptomatic bradycardia, ventricular ectopy, or dysrhythmias should be treated with digoxin immune Fab. Digoxin immune Fab is also indicated for patients with chronic toxicity with ventricular ectopy or symptomatic bradycardia. If digoxin imm... | Severe Chronic Digoxin Toxicity | |
For mild and moderate toxicity, treat with supportive care, as the patient eventually metabolizes the phenytoin. If the patient is awake and alert, administer a dose of activated charcoal. Protect the patient from self-injury secondary to ataxia. | Mild to Moderate Phenytoin Toxicity | |
For large phenytoin Overdoses, treat with supportive care, which may include intubation for comatose patients. If seizures do occur, treat with benzodiazepines and evaluate for other causes of seizures. | Severe Phenytoin Toxicity | |
Patients presenting with severe acidosis, signs or symptoms of visual changes, or depressed level of consciousness should be started immediately on an ADH inhibitor and intravenous folate. Hemodialysis should be initiated and should be continued until the methanol concentration is undetectable and the serum pH is norm... | Severe Methanol toxicity | |
Obtain a methanol level, serum chemistry, and a serum pH. A thorough visual exam should be performed, including visual acuity. An elevated osmolar gap suggests the presence of methanol or another alcohol but cannot be used to rule out a significant exposure. If a methanol concentration is readily available (results kno... | Mild Methanol Toxicity | |
Obtain a methanol level, serum chemistry, and a serum pH. A thorough visual exam should be performed, including visual acuity. An elevated osmolar gap suggests the presence of methanol or another alcohol but cannot be used to rule out a significant exposure. If a methanol concentration is readily available (results kno... | Moderate Methanol toxicity | |
ORAL: Obtain an acetaminophen concentration, 4 hours after ingestion or as soon as possible thereafter. If the time of ingestion is known and the acetaminophen concentration is measured between 4 and 24 hours postingestion, the patient can be risk stratified using the Rumack-Matthew Nomogram. If it is not possible to m... | Mild Acute Acetaminophen Toxicity | |
ORAL: Obtain an acetaminophen concentration, 4 hours after ingestion or as soon as possible thereafter. If the time of ingestion is known and the acetaminophen concentration is measured between 4 and 24 hours postingestion, the patient can be risk stratified using the Rumack-Matthew Nomogram. If it is not possible to m... | Moderate Acute Acetaminophen Toxicity | |
1) Patients who present late after an acute acetaminophen ingestion (greater than 36 hours) may have significant liver injury and even liver failure (INR greater than 1.5, acidosis or encephalopathy). Intubate patients with altered mental status and resuscitate hypotensive patients with crystalloid and adrenergic vasop... | Severe Acute Acetaminophen Toxicity | |
1) Stop acetaminophen therapy. The vast majority of repeated supratherapeutic ingestions of acetaminophen can be managed with symptomatic and supportive care. Treatment should be initiated with n-acetylcysteine (NAC) if the patient’s acetaminophen concentration is greater than or equal to 20 mcg/mL and/or if liver enzy... | Mild to Moderate Acetaminophen-Repeated Supratherapeutic Toxicity | |
Aggressive symptomatic and supportive care in addition to n-acetylcysteine therapy must be undertaken in severe toxicity. Intubate patients with respiratory compromise or encephalopathy. Maintain blood pressure with IV fluids and pressors if needed. Call your local poison center and or transplant team for assistance t... | Severe Acetaminophen-Repeated Supratherapeutic Toxicity | |
Most patients with dermal exposure will do well if irrigated immediately. There is no evidence that any products are more effective than water. Patients with ophthalmic exposure should have each eye irrigated with 1 L of normal saline, LR or water. | Mild to Moderate Oral/Parenteral Toothpaste or Fluoride Exposure | |
Patients with ophthalmic exposure should have each eye irrigated with 1 L of normal saline, LR or water. | Severe Ocular Toothpaste or Fluoride Exposure | |
Patients should be treated in a stepwise manner based on their response to therapy. The initial treatment for pain from dermal exposure is topical calcium. One method for making a gel is to mix calcium gluconate with methylcellulose or water-soluble lubricant in a 1:2 ratio. Apply the gel to the affected areas as frequ... | Mild to Moderate Dermal Toothpaste or Fluoride Exposure | |
Early administration of high doses of calcium salts and magnesium may be life-saving. Administer sufficient calcium to maintain serum concentrations in the high-normal range. | SYSTEMIC Fluoride POISONING | |
An initial salicylate level should be obtained and repeated every 1 to 2 hours until a clear peak and decline in concentration is observed. Concentrations greater than 30 mg/dL and rising should be treated with urine alkalinization. The presence of a large anion gap metabolic acidosis or altered mental status indicates... | MILD TO MODERATE Salicylate TOXICITY | |
Patients with severe poisoning should be continued on urine alkalinization. Hemodialysis should be strongly considered. Relative indications for hemodialysis include: renal failure, congestive heart failure, altered mental status, seizures, evidence of cerebral edema, worsening acidosis despite adequate resuscitation, ... | Severe Acute Salicylate Toxicity | |
Patients with severe poisoning should be continued on urine alkalinization. Hemodialysis should be strongly considered. Relative indications for hemodialysis include: renal failure, congestive heart failure, altered mental status, seizures, evidence of cerebral edema, worsening acidosis despite adequate resuscitation, ... | Severe Chronic Salicylate Toxicity | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | Mild to Moderate Doxylamine Toxicity | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | Severe Doxylamine Toxicity | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Chlorpheniramine TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE Chlorpheniramine TOXICITY | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Diphenhydramine TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE Diphenhydramine TOXICITY | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Hydroxyzine( Vistaril) TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE HHydroxyzine( Vistaril) TOXICITY | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Cetirizine TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE Cetirizine TOXICITY | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Levocetirizine TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE Levocetirizine TOXICITY | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Fexofenadine TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE Fexofenadine TOXICITY | |
Somnolence, anticholinergic effects (ie, mydriasis, flushing, fever, dry mouth, and decreased bowel sounds), tachycardia, mild hypertension, and nausea and vomiting are common after Overdose. Agitation, confusion, and hallucinations may develop with moderate poisoning. | MILD TO MODERATE Desloratadine TOXICITY | |
Severe effects may include agitated delirium, psychosis, seizures, coma, hypotension, QRS widening, and ventricular dysrhythmias, including torsade de pointe but are generally only reported in adults after very large, deliberate ingestions. Rhabdomyolysis and renal failure may rarely develop in patients with prolonged ... | SEVERE Desloratadine TOXICITY | |
The majority of antihistamine Overdoses requires only supportive care; give activated charcoal if patient presents shortly after ingestion; sedate with benzodiazepines for agitation and delirium. Tachycardia is generally mild and well tolerated, and does not usually require specific treatment. Physostigmine can be used... | MILD TO MODERATE Loratadine TOXICITY | |
Orotracheal intubation for airway protection should be performed early. Gastric lavage may be of benefit, if the patient presents soon after a large ingestion; administer activated charcoal as well. GI decontamination should be performed only in patients who can protect their airway or who are intubated. Severe deliriu... | SEVERE Loratadine TOXICITY | |
Most patients will have no symptoms, but patients with mild orthostatic hypotension can be treated by remaining prone. Those who remain hypotensive can be treated with IV fluids | Mild to Moderate Captopril Toxicity | |
Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if the patient presents with circulatory collapse. Correct severe hyperkalemia using standard treatments such as glucose, insulin, calcium, sodium bicarbonate, sodium polystyrene sulfate and hemodialysis. | Severe Captopril Toxicity | |
Most patients will have no symptoms, but patients with mild orthostatic hypotension can be treated by remaining prone. Those who remain hypotensive can be treated with IV fluids. | Mild to Moderate Enalapril Toxicity | |
Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if the patient presents with circulatory collapse. Correct severe hyperkalemia using standard treatments such as glucose, insulin, calcium, sodium bicarbonate, sodium polystyrene sulfate and hemodialysis. | Severe Enalapril Toxicity | |
Most patients will have no symptoms, but patients with mild orthostatic hypotension can be treated by remaining prone. Those who remain hypotensive can be treated with IV fluids. | Mild to Moderate Fosinopril Toxicity | |
Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if the patient presents with circulatory collapse. Correct severe hyperkalemia using standard treatments such as glucose, insulin, calcium, sodium bicarbonate, sodium polystyrene sulfate and hemodialysis | Severe Fosinopril Toxicity | |
Most patients will have no symptoms, but patients with mild orthostatic hypotension can be treated by remaining prone. Those who remain hypotensive can be treated with IV fluids. | Mild to Moderate Lisinopril Toxicity | |
Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if the patient presents with circulatory collapse. Correct severe hyperkalemia using standard treatments such as glucose, insulin, calcium, sodium bicarbonate, sodium polystyrene sulfate and hemodialysis. | Severe Lisinopril Toxicity | |
Most patients will have no symptoms, but patients with mild orthostatic hypotension can be treated by remaining prone. Those who remain hypotensive can be treated with IV fluids. | Mild to Moderate Ramipril Toxicity | |
Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if the patient presents with circulatory collapse. Correct severe hyperkalemia using standard treatments such as glucose, insulin, calcium, sodium bicarbonate, sodium polystyrene sulfate and hemodialysis. | Severe Ramipril Toxicity | |
Most patients will have no symptoms, but patients with mild orthostatic hypotension can be treated by remaining prone. Those who remain hypotensive can be treated with IV fluids | Mild to Moderate Trandolapril Toxicity | |
Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if the patient presents with circulatory collapse. Correct severe hyperkalemia using standard treatments such as glucose, insulin, calcium, sodium bicarbonate, sodium polystyrene sulfate and hemodialysis | Severe Trandolapril Toxicity | |
Treatment is symptomatic and supportive. Treat significant vomiting and diarrhea with IV fluids; administer antiemetics, as needed. HYPERSENSITIVITY REACTION: Administer antihistamines, with or without inhaled beta agonists, corticosteroids or epinephrine. | Mild to Moderate Amoxicillin Toxicity | |
Acute anaphylaxis is more likely to occur after parenteral exposure, but may develop with all routes. Administer oxygen, aggressive airway management, antihistamines, epinephrine, corticosteroids, ECG monitoring, and IV fluids. Dysrhythmias should be treated with standard antiarrhythmic drugs, if necessary. SEIZURES: I... | Severe Oral Amoxicillin Toxicity | |
Treatment is symptomatic and supportive. Treat significant vomiting and diarrhea with IV fluids; administer antiemetics, as needed. HYPERSENSITIVITY REACTION: Administer antihistamines, with or without inhaled beta agonists, corticosteroids or epinephrine | Mild to Moderate Ampicillin Toxicity | |
Acute anaphylaxis is more likely to occur after parenteral exposure, but may develop with all routes. Administer oxygen, aggressive airway management, antihistamines, epinephrine, corticosteroids, ECG monitoring, and IV fluids. Dysrhythmias should be treated with standard antiarrhythmic drugs, if necessary. SEIZURES: I... | Severe Ampicillin Toxicity | |
Monitor serum electrolytes, renal function and ethylene glycol concentration. A peak ethylene glycol concentration < 20 mg/dL is commonly considered nontoxic. If the serum ethylene glycol concentration is >20 mg/dL, or there is a metabolic acidosis, or a history of a potentially toxic ingestion and ethylene glycol conc... | Mild to Moderate Ethylene Glycol Toxicity | |
CNS depression may require intubation; adequate minute ventilation must be insured to prevent abrupt worsening of acidemia. Alcohol-induced vasodilation and vomiting may lead to hypotension requiring fluid resuscitation. Alcohol dehydrogenase (ADH) inhibition is the most specific treatment for patients with severe ethy... | Severe Ethylene Glycol Toxicity | |
Patients with mild to moderate toxicity can be treated with supportive care. Intravenous fluids should be given to maintain urine output and supplemental oxygen applied | Mild to Moderate Benzocaine Toxicity | |
Patients with evidence of end-organ ischemia should be treated with methylene blue regardless of the methemoglobin concentration. However, patients are unlikely to have end-organ ischemia with concentrations less than 20%. Treatment with methylene blue should result in resolution of all symptoms attributable to methemo... | Severe Benzocaine Toxicity | |
For management of mild to moderate toxicity, good supportive care is all that is needed. Treatment may include fluids and antiemetics for patients with nausea and vomiting or benzodiazepines for agitation. For drug-induced dystonia, treatment includes benztropine and diphenhydramine | Mild to Moderate Aripiprazole Toxicity | |
Mainstay of treatment is good supportive care, including airway management for patients with severe CNS sedation and fluid and vasopressors for hypotension. For patients with neuroleptic malignant syndrome, standard treatments include sedation with benzodiazepines, bromocriptine, and dantrolene (used in severe cases), ... | Severe Aripiprazole Toxicity | |
Most ibuprofen toxicity resolves with supportive care. Otherwise healthy patients with a history of ibuprofen poisoning generally require only supportive care and fluid and electrolyte replacement | Mild to Moderate Ibuprofen Toxicity | |
Maintain an open airway and support ventilation. Treat seizures with benzodiazepines, hypotension with fluids and adrenergic vasopressors, and coma with intubation. Monitor ECG and arterial blood gases in patients with severe toxicity. | Severe Ibuprofen Toxicity | |
Patients who have asymptomatic bradycardia can be admitted and observed with telemetry. Obtain peripheral intravenous access and monitor ECG. Mild hypotension may only require treatment with intravenous fluid administration. | Mild to Moderate Felodipine Toxicity | |
Patients with bradycardia and hypotension require standard ACLS treatment. Place a central line and consider placement of an arterial line. Standard first line treatment includes atropine for bradycardia although in a serious poisoning it is rarely effective. High dose insulin and dextrose have been effective in animal... | Severe Felodipine Toxicity | |
Treat GI distress and administer IV fluids. Manage mild hypotension with IV fluids. | Mild to Moderate Indomethacin Toxicity | |
Administer IV fluids, treat GI distress and monitor for GI bleeding. Patients with severe altered mental status may require intubation. Treat seizures with IV benzodiazepines; barbiturates or propofol may be needed if seizures persist or recur. Treat severe hypotension with IV 0.9% NaCl at 10 to 20 mL/kg. Add dopamine ... | Severe Indomethacin Toxicity | |
Primarily supportive care; activated charcoal may be helpful in patients presenting shortly after ingestion. Give benzodiazepines titrated to effect for anxiety and seizures. | Mild to Moderate Sertraline Toxicity | |
Consider activated charcoal if patients present early after ingestion. If significant CNS depression occurs, intubate the patient for airway protection before giving charcoal. Consider intravenous lipid therapy early for patients with ventricular dysrhythmias or hypotension. Give benzodiazepines for seizures. Treat ser... | Severe Sertraline Toxicity | |
Most patients require only supportive care. Control agitation and confusion with either benzodiazepines or serotonin antagonist such as cyproheptadine or chlorpromazine. Manage mild hypotension with IV fluids. Hypertension and tachycardia are generally mild and well tolerated, and do not require specific treatment. | Mild to Moderate Celexa (Citalopram) Toxicity | |
Early intubation, neuromuscular paralysis, ventilation assistance, and aggressive cooling should be performed if the patient presents with respiratory depression, severe muscle rigidity, and severe hyperthermia. Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if patient presen... | Severe Celexa (Citalopram) Toxicity | |
Most patients require only supportive care. Control agitation and confusion with either benzodiazepines or serotonin antagonist such as cyproheptadine or chlorpromazine. Manage mild hypotension with IV fluids. Hypertension and tachycardia are generally mild and well tolerated, and do not require specific treatment. | MILD TO MODERATE Escitalopram (Lexapro) TOXICITY | |
Early intubation, neuromuscular paralysis, ventilation assistance, and aggressive cooling should be performed if the patient presents with respiratory depression, severe muscle rigidity, and severe hyperthermia. Adequate circulatory support with IV fluids and vasopressors (if needed) should be assured if patient presen... | SEVERE Escitalopram (Lexapro) TOXICITY | |
Primarily supportive care; a single dose of activated charcoal may be helpful in patients presenting shortly after ingestion | MILD TO MODERATE Fluoxetine TOXICITY | |
Treatment of gabapentin exposure is largely supportive with mild/moderate symptoms. An observation period of 4 to 6 hours is reasonable | MILD TO MODERATE Gabapentin TOXICITY | |
Treatment of gabapentin exposure is largely supportive in nature with careful attention to airway protection in severe cases. Hypotension is usually mild responding to intravenous fluid boluses. If hypotension persists, administer dopamine or norepinephrine. Admit all severely symptomatic patients. Treat seizures with ... | SEVERE Gabapentin TOXICITY | |
Supportive care is the mainstay of treatment. Administer naloxone for CNS or respiratory depression. | MILD TO MODERATE Loperamide (Imodium) TOXICITY | |
Supportive care is the mainstay of treatment. Administer oxygen and monitor for respiratory and CNS depression. The AACT and AAPCC loperamide position statement endorsed by the ACMT, recommends: Consider a starting dose of 0.4 mg naloxone in patients with respiratory depression after acute Overdose, with dose titration... | SEVERE Loperamide (Imodium) TOXICITY | |
Primarily supportive care; single dose activated charcoal is advised in patients presenting shortly after an ingestion of more than 3 mg. | MILD TO MODERATE acute L-thyroxine TOXICITY | |
Give activated charcoal if a patient presents early after ingestion of more than 3 mg. In case of seizure, severe agitation, or significant CNS depression, perform orotracheal intubation for airway protection before giving charcoal. Administer benzodiazepines to treat seizures and agitation. Signs of catecholamine exce... | SEVERE acute L-thyroxine TOXICITY | |
In case of seizure, severe agitation, or significant CNS depression, perform orotracheal intubation for airway protection before giving charcoal. Administer benzodiazepines to treat seizures and agitation. Signs of catecholamine excess such as significant hypertension and tachycardia are effectively treated with propra... | CHRONIC L-thyroxine TOXICITY |
End of preview. Expand in Data Studio
No dataset card yet
- Downloads last month
- 4